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Cat. No.: LwaCas13aLyo-200 (for 200pmol)

Cat. No.: LwaCas13aLyo-2k (for 2000pmol)

Cat. No.: LwaCas13aLyo-10k (for 10000pmol)

Description

LwaCas13a (also known as C2c2) is a crRNA-guided RNA endonuclease dependent on crRNA alone, originating from the Leptotrichia wadei strain. It can specifically recognize and cleave target single-stranded RNA, with relatively lenient requirements for the PFS sequence. Additionally, Cas13a exhibits trans-cleavage activity (i.e., collateral cleavage activity). Upon formation of a ternary complex comprising LwaCas13a protein, crRNA, and target RNA, the enzyme is activated to cleave non-specific sequences of single-stranded RNA in the system, breaking down any sequence of single-stranded RNA. This activity has also been utilized in the development of rapid detection kits for target nucleic acids.

This lyophilized format enables convenient room‑temperature shipping.

Applications

• Real-time Fluorescent Detection 
• Colloidal gold chromatography
• Gene editing
• Molecular diagnosis

Storage 

Ship at room temperature. Store at –20 °C for a minimum shelf life of 1 year.