LtrCas13a (C2c2) Nuclease
$704.00 - $1,412.00
All products have special prices for bulk purchase, please contact us for more details if required.
Cat. No.: LtrCas13a-100 (for 100pmol)
Cat. No.: LtrCas13a-1k (for 1000pmol)
LtrCas13a Nuclease (also known as C2c2) is a crRNA-guided RNA endonuclease derived from the Leptotrichia trevisanii strain. In the presence of a PFS sequence in the target single-stranded RNA, it can selectively recognize and cleave the target RNA. Additionally, Cas13a exhibits trans-cleavage activity (also known as collateral cleavage activity). That is, when the LtrCas13a protein forms a ternary complex with crRNA and target RNA, it is activated to perform trans-cleavage activity against non-specific sequence single-stranded RNA, resulting in the cleavage of any sequence single-stranded RNA in the system. This activity has also been utilized in the development of rapid diagnostic kits for target nucleic acids.
- Real-time Fluorescent Detection
- Colloidal gold chromatography
- Gene editing
- Molecular diagnosis
The minimum shelf life is 1 year at -20°C.
SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.
Related: Synthetic sgRNAs
SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory