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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.

from China, for the World

for Superior Biology Services since 2000

  • Home
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    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Enzymes
  • POCT 
    • Integrated POCT Platform
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    • Freeze-Drying System
  • About 
    • About SBS
    • Solutions
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    • Legal Statement
  • Contact
  • …  
    • Home
    • Products 
      • All Products
      • Custom Services
      • Catalog Products
      • Innovative Systems
      • Nucleic Acid Related
      • Enzymes
    • POCT 
      • Integrated POCT Platform
      • LAMP
      • RPA
      • CRISPR
      • DNA-Free Enzymes
      • Lateral Flow System
      • Freeze-Drying System
    • About 
      • About SBS
      • Solutions
      • Achievements
      • Legal Statement
    • Contact
    • Login
tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.

from China, for the World

for Superior Biology Services since 2000

  • Home
  • Products 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Enzymes
  • POCT 
    • Integrated POCT Platform
    • LAMP
    • RPA
    • CRISPR
    • DNA-Free Enzymes
    • Lateral Flow System
    • Freeze-Drying System
  • About 
    • About SBS
    • Solutions
    • Achievements
    • Legal Statement
  • Contact
  • …  
    • Home
    • Products 
      • All Products
      • Custom Services
      • Catalog Products
      • Innovative Systems
      • Nucleic Acid Related
      • Enzymes
    • POCT 
      • Integrated POCT Platform
      • LAMP
      • RPA
      • CRISPR
      • DNA-Free Enzymes
      • Lateral Flow System
      • Freeze-Drying System
    • About 
      • About SBS
      • Solutions
      • Achievements
      • Legal Statement
    • Contact
    • Login
Beijing SBS Genetech Co.,Ltd.
  • DNA-Free Enzymes

    for Ultra-Pure Molecular Workflows

    Eliminating host DNA contamination to improve accuracy, sensitivity, and reliability in PCR, qPCR, NGS, and advanced molecular diagnostics

  • What are DNA-Free Enzymes?

    Ultra-pure molecular biology enzymes designed to minimize residual DNA contamination and improve the reliability of highly sensitive molecular workflows

    Conventional Enzyme Production - SBS Genetech

    DNA-Free enzymes are specially purified molecular biology enzymes designed to minimize residual DNA contamination from recombinant enzyme production processes. During conventional enzyme manufacturing, trace amounts of host-derived genomic DNA or plasmid DNA may remain after purification and become a potential source of background contamination in highly sensitive molecular assays.

    While trace DNA contamination may have limited impact in routine molecular biology applications, it can become a significant challenge in highly sensitive workflows. Applications including PCR, qPCR, digital PCR, next-generation sequencing (NGS), and molecular diagnostics require extremely low background levels, where even small amounts of contaminating DNA may contribute to unwanted amplification signals or inaccurate results.

    By applying advanced purification strategies and rigorous quality control, DNA-Free enzymes help create cleaner reaction environments with improved signal-to-noise ratios and greater assay confidence. These ultra-pure enzyme solutions enable researchers and diagnostic developers to achieve more reliable performance in contamination-sensitive molecular workflows.

  • Key Challenge

    Trace DNA contamination can compromise ultra-sensitive molecular assays by increasing background signals and false-positive risk.

    Key Benefit

    DNA-Free enzymes provide cleaner reaction systems for more accurate and reliable molecular detection.
  • Advanced DNA-Free Enzyme Technology

    A comprehensive development workflow combining optimized purification, enzyme activity preservation, and rigorous quality control to deliver ultra-clean molecular biology reagents

    SBS DNA-Free Enzyme - SBS Genetech

    Developing DNA-Free enzymes requires a precise balance between effective DNA contamination removal and preservation of enzyme functionality. Simply reducing residual DNA is not sufficient; molecular biology enzymes must maintain their catalytic activity, stability, and compatibility with downstream applications.

    SBS Genetech applies optimized purification strategies throughout the enzyme manufacturing process to minimize residual host-derived DNA while maintaining robust enzymatic performance. Our workflow integrates advanced purification, process optimization, and functional evaluation to ensure consistent quality across different enzyme classes.

    Through this integrated technology platform, SBS DNA-Free enzymes provide reliable performance for contamination-sensitive workflows, including PCR, qPCR, digital PCR, NGS library preparation, and molecular diagnostics.

  • Verified Ultra-Low DNA Background

    Rigorous quality testing confirms minimal residual DNA contamination while maintaining reliable enzyme performance for contamination-sensitive molecular workflows

    Ct >40 Validation

    qPCR-based testing demonstrates extremely low residual DNA background in DNA-Free enzymes.

    Ultra-Low DNA Background

    Advanced purification processes reduce DNA impurities that may interfere with sensitive molecular assays.

    Maintained Enzyme Performance

    DNA removal is achieved while preserving enzyme activity, stability, and downstream application performance.

    Rigorous Quality Control

    Comprehensive quality assessment ensures reliable performance for research and diagnostic workflows.

  • 1
    Sample Preparation

    DNA-Free enzymes are prepared for residual DNA assessment under standardized testing conditions.

    2
    qPCR-Based Detection

    Sensitive qPCR analysis is performed to detect potential residual DNA signals from enzyme preparations.

    3
    Signal Analysis

    Amplification profiles and Ct values are evaluated to determine the level of background DNA contamination.

    4
    Performance Validation

    Results confirm ultra-low DNA background and reliable performance of DNA-Free enzymes in sensitive molecular workflows.

  • Applications of DNA-Free Enzymes

    Supporting contamination-sensitive workflows across molecular diagnostics, nucleic acid research, and advanced molecular biology applications

    Molecular Diagnostics

    DNA-Free enzymes help reduce background signals and improve confidence in highly sensitive diagnostic assays, including pathogen detection and point-of-care molecular testing.

    PCR & qPCR Applications

    Ultra-low DNA background enables cleaner amplification reactions and improved reliability for PCR-based workflows requiring high analytical sensitivity.

    NGS Library Preparation

    Minimizing contaminating DNA improves the accuracy and consistency of sequencing workflows, especially in low-input and high-sensitivity applications.

    Sensitive Molecular Biology Research

    DNA-Free enzymes provide reliable performance for applications where background DNA contamination may interfere with experimental results.

  • DNA-Free Enzyme Portfolio

    A comprehensive collection of DNA-Free molecular biology enzymes designed for contamination-sensitive research and diagnostic workflows

    product image
    Buy now
    DNA-Free Taq DNA Polymerase
    $160.00 - $520.00
    $650.00
    product image
    Buy now
    DNA-Free HS-Taq DNA Polymerase
    $112.00 - $2,480.00
    $3,100.00
    product image
    Buy now
    DNA-Free HS HiFi Taq DNA Polymerase
    $160.00 - $3,200.00
    $4,000.00
    product image
    Buy now
    DNA-Free Pfu DNA Polymerase
    $160.00 - $800.00
    $1,000.00
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    Buy now
    DNA-Free HS Pfu DNA Polymerase
    $160.00 - $5,250.00
    product image
    Buy now
    DNA-Free HSTaq qPCR 2× SuperMix (SYBR Green)
    $248.00 - $2,600.00
    $3,250.00
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    Buy now
    DNA-Free HSTaq qPCR 2× SuperMix (Taqman)
    $248.00 - $2,600.00
    $3,250.00
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    Buy now
    DNA-Free Thermo-stable M-MLV Reverse Transcriptase (RNase H-)
    $450.00 - $13,500.00
    product image
    Buy now
    DNA-Free Deep Tli (exo-) DNA Polymerase
    $160.00 - $3,200.00
    $4,000.00
    product image
    Buy now
    DNA-Free Deep Tli DNA Polymerase
    $160.00 - $3,200.00
    $4,000.00
    product image
    Buy now
    DNA-Free Tli (exo-) DNA Polymerase
    $160.00 - $3,200.00
    $4,000.00
    product image
    Buy now
    DNA-Free Tli DNA Polymerase
    $160.00 - $3,200.00
    $4,000.00
    product image
    Buy now
    DNA-Free Tth DNA Polymerase
    $160.00 - $2,400.00
    $3,000.00
    product image
    Buy now
    DNA-Free RNase T
    $360.00 - $960.00
    $1,200.00
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    Buy now
    DNA-Free One-Step RT-qPCR 2× SuperMix (Taqman)
    $120.00 - $3,600.00
    $4,500.00
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    Buy now
    DNA-Free One-Step RT-qPCR 2× SuperMix (SYBR Green)
    $104.00 - $3,120.00
    $3,900.00
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    Buy now
    DNA-Free HSTaq-D UDG qPCR 2× SuperMix (SYBR Green)
    $120.00 - $4,000.00
    $5,000.00
    product image
    Buy now
    DNA-Free HSTaq UDG qPCR 2× SuperMix (Taqman)
    $128.00 - $3,840.00
    $4,800.00
    product image
    Buy now
    DNA-Free HSTaq UDG qPCR 2× SuperMix (SYBR Green)
    $100.00 - $2,800.00
    $3,500.00
    product image
    Buy now
    DNA-Free One-Step High Temperature RT-PCR 2× SuperMix
    $112.00 - $3,200.00
    $4,000.00
  • Custom DNA-Free Enzyme Solutions

    Partner with SBS Genetech to develop DNA-Free enzymes tailored to your research, diagnostic, and commercial manufacturing requirements

    Beyond our standard DNA-Free enzyme portfolio, SBS Genetech provides customized development services for researchers, diagnostic developers, and industrial partners. From enzyme selection and expression optimization to DNA-free purification and quality validation, our team works closely with customers to deliver solutions tailored to specific applications and performance requirements.

    Whether you require a customized DNA-Free polymerase, reverse transcriptase, isothermal amplification enzyme, or large-scale OEM manufacturing, SBS offers flexible development and production capabilities to support projects from early research through commercial deployment.

  • Custom Enzyme Development

    Tailored enzyme selection, expression optimization, and DNA-free purification for specific application requirements.

    OEM & Bulk Manufacturing

    Scalable manufacturing solutions for research reagents, molecular diagnostics, and commercial production.

    Technical Collaboration

    Application-specific optimization, performance validation, and dedicated technical support throughout development.

  • Trusted by Researchers Worldwide

    SBS Genetech products have supported thousands of peer-reviewed publications across molecular biology, diagnostics, genomics, synthetic biology, and life science research

    Journals Using SBS Genetech Products: Science, Cell, Cancer Cell, Cell Metabolism, Immunity, Nucleic Acids Research, Advanced Science, etc.

    Journals Using SBS Genetech Products

    Universities Using SBS Genetech Products: Harvard University, Imperial College London, National University of Singapore, Cornell University, Tsinghua University, etc

    Universities Using SBS Genetech Products

  • Learn More About DNA-Free Enzymes

    Explore technical articles, application guides, and best practices for DNA-free molecular biology workflows

    Customized DNA-Free Enzymes for Precision Research | SBS Genetech
    May 5, 2025
    As a pioneering enterprise in China’s life sciences sector, Beijing SBS Genetech Co., Ltd. has been dedicated to delivering advanced scientific solutions to researchers worldwide. Since our founding in 2000, we have steadily expanded from custom oligonucleotide synthesis, gene synthesis, and...
    Read more...
    DNA-Free HS HiFi Taq DNA Polymerase by SBS Genetech: Enhancing PCR Accuracy and Reliability
    March 9, 2025
    DNA-Free HS HiFi Taq DNA Polymerase, developed by SBS Genetech, is a cutting-edge enzyme designed to enhance the accuracy and reliability of PCR (Polymerase Chain Reaction) applications. This enzyme is specifically engineered to minimize the risk of contamination with bacterial and human DNA,...
    Read more...
    DNA-Free M-MLV Reverse Transcriptase by SBS Genetech: Elevating RNA Research with High Precision
    February 6, 2025
    DNA-Free M-MLV Reverse Transcriptase by SBS Genetech is a game-changing enzyme designed to elevate the accuracy and reliability of RNA-based research. Engineered with cutting-edge technology to ensure minimal contamination with bacterial and human DNA, this enzyme is an invaluable asset for...
    Read more...
  • Contact

    For more information, please fill out the provided form or contact us directly by E-mail

    Room 11E, Building 2
    No.2 Shangdi Information Road
    Haidian District
    Beijing 100085 China
    (0086-10)62969345/46
    (0086-10)62969345/46
    tech@sbsbio.com

SBS Genetech © Copyright 2000-2026

from China, for the World

for Superior Biology Services since 2000

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