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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.
broken image

from China, for the World

for Superior Biology Services since 2000

  • Home
  • Product 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Natural Compounds
    • Synthetic Biology
    • Enzymes
  • POCT Solution 
    • LAMP
    • RPA
    • CRISPR
    • DNA-Free Enzymes
    • Freeze-Drying System
    • Lateral Flow System
  • About 
    • About SBS
    • Achievements
    • Ecosystem
    • Legal Statement
  • Contact
  • …  
    • Home
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      • All Products
      • Custom Services
      • Catalog Products
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      • Synthetic Biology
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    • POCT Solution 
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      • RPA
      • CRISPR
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      • Freeze-Drying System
      • Lateral Flow System
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LbCas12a (Cpf1) Nuclease

LbCas12a (Cpf1) Nuclease

$300.00 - $1,000.00
LbCas12a (also known as LbCpf1) is a crRNA-guided DNA endonuclease derived from the Lachnospiraceae bacterium ND2006 strain. In the presence of a PAM (TTTN) sequence on the target double-stranded DNA, LbCas12a specifically cleaves the target DNA, inducing double-strand breaks and generating sticky ends. Additionally, LbCas12a cleaves single-stranded DNA targets in a PAM-independent manner. Furthermore, both double-stranded and single-stranded DNA targets activate the trans- cleavage activity of LbCas12a (i.e., collateral cleavage activity). Upon formation of a ternary complex comprising LbCas12a enzyme, crRNA, and target DNA, the enzyme is activated to cleave non-specific sequences of ssDNA in the system. Consequently, LbCas12a enzyme can be utilized not only for specific cleavage of dsDNA in vitro but also for rapid detection of target nucleic acids.
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All products have special prices for bulk purchase, please contact for more details if required.

 

Cat. No.: LbCas12a-2k (for 2000pmol)

Cat. No.: LbCas12a-10k (for 20000pmol)

 

We also provide lyophilized LbCas12a, please visit Cas12a Nuclease (Lyophilized).

 

Description

LbCas12a (also known as LbCpf1) is a crRNA-guided DNA endonuclease derived from the Lachnospiraceae bacterium ND2006 strain. In the presence of a PAM (TTTN) sequence on the target double-stranded DNA, LbCas12a specifically cleaves the target DNA, inducing double-strand breaks and generating sticky ends. Additionally, LbCas12a cleaves single-stranded DNA targets in a PAM-independent manner. Furthermore, both double-stranded and single-stranded DNA targets activate the trans- cleavage activity of LbCas12a (i.e., collateral cleavage activity). Upon formation of a ternary complex comprising LbCas12a enzyme, crRNA, and target DNA, the enzyme is activated to cleave non-specific sequences of ssDNA in the system. Consequently, LbCas12a enzyme can be utilized not only for specific cleavage of dsDNA in vitro but also for rapid detection of target nucleic acids.

 

Storage

The minimum shelf life is 1 year at -20°C.

 

SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.

 

Related: 

  • Synthetic sgRNAs
  • Cas12a Nuclease (Lyophilized)
  • Cas12b Nuclease (Lyophilized)
  • Cas13a Nuclease (Lyophilized)
  • Cas14a1 Nuclease (Lyophilized)
  • Cas9 Nuclease (with NLS)
  • Cas9 HF-NLS (SpCas9 HF-NLS)
  • CRISPR-dCas9 Nuclease
  • dCas9 NLS
  • spCas9
  • SpdCas9
  • spCas9-NG
  • SpRYCas9
  • Cas9 Nickase (H840A) NLS
  • Cas9 Nickase (D10A) NLS
  • TsCas12a
  • OsCas12a
  • HkCas12a
  • BoCas12a
  • AsCas12a
  • FnCas12a
  • LbCas12a (Cpf1) Nuclease
  • Enhanced LbaCas12a (Cpf1)
  • Lb5Cas12a (Cpf1) Nuclease
  • SuCas12a2 Nuclease
  • AaCas12b
  • AacCas12b
  • AapCas12b
  • BrCas12b
  • LwCas13a
  • LtrCas13a (C2c2) Nuclease
  • LwaCas13a (C2c2) Nuclease
  • EiCsm6
  • PfAgo
  • TtAgo
  • T7 Endonuclease I

 

 

 

Only for research and not intended for treatment of humans or animals
 
 

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

 

 

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

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