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Cas9 Nuclease (with NLS, 50μg)

Cas9 Nuclease (with NLS, 50μg)

Cas9 Nuclease is a recombinant Streptococcus pyogenes Cas9 (wt) protein. A nucleic localization signal (NLS) is added which can be used for genome editing by inducing site-specific DNA double-stranded breaks. Cas9 protein can form ribonucleoprotein (RNP) complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the NLS.
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All products have special prices for bulk purchase, please contact for more details if required.

 

Cat. No.: NCas-500

 

Advantages

Compared with the mRNA or plasmid systems:

  • Transcription and translation processes are not required

  • Avoiding the risk of inserting foreign DNA into the genome

  • Minimizing the off target effect

 

 

Applications

  • in vitro cleavage assay

  • RNP complex transfection 

  • microinjection

 

Storage

Recommended to be stored at -20°C.

 

SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.

 

Related: Synthetic sgRNAs

 

 

Only for research and not intended for treatment of humans or animals
 
 

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

 

 

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

  • Featured Publications

    We are honored to create value for our customers and facilitate the development of science

    Congratulations to Our Customer for Published in Nature Communications (IF: 18)!
    October 1, 2023
    On September 28th, a breakthrough paper was published by researchers from Sun Yat-sen University...
    Read more...
    Congratulations to Our Customer for Published in Advanced Materials (IF: 32)!
    August 27, 2023
    On August 17th, a research paper entitled "Cellular Membrane-Engineered Nanovesicles as Three...
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    Congratulations to Our Customer for Published in Molecular Plant (IF: 22)!
    April 12, 2023
    On April 6th, a research paper entitled "Phosphorylation of OsRbohB by the CaM-dependent protein...
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