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Cas9 Nuclease (with NLS, 50μg)
Cas9 Nuclease is a recombinant Streptococcus pyogenes Cas9 (wt) protein. A nucleic localization signal (NLS) is added which can be used for genome editing by inducing site-specific DNA double-stranded breaks. Cas9 protein can form ribonucleoprotein (RNP) complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the NLS.
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All products have special prices for bulk purchase, please contact for more details if required.
Cat. No.: NCas-500
Advantages
Compared with the mRNA or plasmid systems:
Transcription and translation processes are not required
Avoiding the risk of inserting foreign DNA into the genome
Minimizing the off target effect
Applications
in vitro cleavage assay
RNP complex transfection
microinjection
Storage
Recommended to be stored at -20°C.
SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.
Related: Synthetic sgRNAs
Only for research and not intended for treatment of humans or animals
