enLbCas12a Nuclease
$500.00 - $2,120.00
All products have special prices for bulk purchase, please contact for more details if required.
Cat. No.: enLbCas12a-100 (for 100pmol)
Cat. No.: enLbCas12a-1k (for 1000pmol)
Description
enLbCas12a (enhanced LbCas12a) is a high-activity LbCas12a mutant engineered from wild-type LbCas12a endonuclease. Sharing the same mechanism of action as wild-type LbCas12a, enLbCas12a is guided by crRNA to specifically recognize double-stranded DNA bearing the PAM sequence (5’-TTN-3’), resulting in double-stranded DNA breaks with sticky ends. Meanwhile, recognition and cleavage of single-stranded DNA targets by enLbCas12a are PAM-independent. Once enLbCas12a assembles into a ternary complex with crRNA and target DNA, it triggers cleavage of non-specific ssDNA sequences, degrading ssDNA present in the reaction system. Therefore, enLbCas12a can be applied not only for specific cleavage of DNA targets but also for rapid detection of target nucleic acids.
Storage
Recommended to be stored at -20°C.
SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.
Related:
- Synthetic sgRNAs
- Cas12a Nuclease (Lyophilized)
- Cas12b Nuclease (Lyophilized)
- Cas13a Nuclease (Lyophilized)
- Cas14a1 Nuclease (Lyophilized)
- SpCas9 Nuclease (Lyophilized)
- SuCas12a2 Nuclease (Lyophilized)
- Cas9 Nuclease (with NLS)
- Cas9 HF-NLS (SpCas9 HF-NLS)
- CRISPR-dCas9 Nuclease
- dCas9 NLS
- spCas9
- SpdCas9
- spCas9-NG
- SpRYCas9
- Cas9 Nickase (H840A) NLS
- Cas9 Nickase (D10A) NLS
- TsCas12a
- OsCas12a
- HkCas12a
- BoCas12a
- AsCas12a
- FnCas12a
- LbCas12a (Cpf1) Nuclease
- Enhanced LbaCas12a (Cpf1)
- Lb5Cas12a (Cpf1) Nuclease
- SuCas12a2 Nuclease
- AaCas12b
- AacCas12b
- AapCas12b
- BrCas12b
- LwCas13a
- LbuCas13a
- LtrCas13a (C2c2) Nuclease
- LwaCas13a (C2c2) Nuclease
- EiCsm6
- PfAgo
- TtAgo
- T7 Endonuclease I
