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Cas14a1
Cas14a1, an endonuclease, can specifically bind and cleave the target ssDNA under the guidance of tracrRNA:crRNA (or sgRNA).
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All products have special prices for bulk purchase, please contact for more details if required.
Cat. No.: Cas14a1-100 (for 100pmol)
Cat. No.: Cas14a1-1k (for 1000pmol)
Description
Compared with other Cas proteins, the molecular weight of Cas14 protein is generally smaller (400-700aa). Similar to Cas12, Cas14a1 can also bind the target nucleic acid and activate its ssDNA trans cleavage activity, so it is can be applied to the molecular detection of target nucleic acid. However, unlike Cas12, there is no PAM binding requirement for Cas14a1. Also, Cas14a1 cleaves only single-stranded DNA (ssDNA) and not double-stranded DNA or single-stranded RNA.
Applications
- Real-time Fluorescent Detection
- Colloidal gold chromatography
- Gene editing
- Molecular diagnosis
Storage
The minimum shelf life is 1 year at -20°C.
SBS Genetech is recognized as one of the global major leading industry players in Gene Editing by third-party market researchers. For more details, please visit Global Gene Editing Service Market 2019 by Company, Regions, Type and Application, Forecast to 2024.
Related: Synthetic sgRNAs
Only for research and not intended for treatment of humans or animals
