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Methacrylated Sodium Alginate (AlgMA)

Methacrylated Sodium Alginate (AlgMA)

Methacrylated Sodium Alginate (AlgMA) is a photocrosslinkable derivative of natural sodium alginate, a polysaccharide extracted from brown algae and widely used for ion‑responsive gelation with calcium and other divalent cations. By introducing methacryloyl groups, AlgMA retains the excellent biocompatibility and ion‑chelation properties of alginate while gaining rapid light‑induced crosslinking capability under UV or visible light. This enables the formation of hydrogels with significantly enhanced mechanical strength and structural stability compared with traditional ionically crosslinked alginate gels. As a versatile biomaterial for drug delivery, tissue engineering, 3D cell culture, and bio‑3D printing, AlgMA provides a robust platform for constructing customizable hydrogel systems in advanced biomedical and engineering applications.
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Description

Sodium alginate (Alg) is a natural polysaccharide extracted from brown algae, composed of randomly arranged β‑D‑mannuronic acid (M) and α‑L‑guluronic acid (G) units. It can rapidly chelate with divalent cations such as calcium or zinc under mild conditions to form hydrogels, and is widely used in drug delivery, tissue‑engineering scaffolds, and cell microencapsulation.

Our AlgMA is a photosensitive, methacrylated derivative of sodium alginate in which methacryloyl groups are introduced along the polymer chain. This modification preserves the material’s excellent ion‑responsive gelation behavior while adding photocrosslinking capability. In the presence of a photoinitiator, AlgMA can be rapidly cured into hydrogels with mechanical strength and structural stability significantly superior to those of traditional ionically crosslinked alginate gels, greatly expanding its potential in biomedical and engineering applications.

 

Product Advantages

  • High Batch Stability: Standardized manufacturing processes ensure consistent product performance and strong experimental reproducibility.
  • High Purity with Low Residuals: Specialized purification techniques effectively remove small‑molecule residues such as methacrylic acid.
  • Multiple Specifications Available: Options include different viscosity grades and endotoxin levels to meet both research and development needs.
  • Reliable Quality and Storage Stability: When stored under recommended conditions, the product maintains long‑term performance stability.

 

MA Series

 

 

 

Only for research and not intended for treatment of humans or animals

 

 

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SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

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