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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.

from China, for the World

for Superior Biology Services since 2000

  • Products 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Natural Compounds
    • Enzymes
  • POCT 
    • 6 POCT Platforms
    • LAMP
    • RPA
    • CRISPR
    • Freeze-Drying System
    • Lateral Flow System
    • DNA-Free Enzymes
    • Pathogen Detection
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    • Synthetic Biology
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Methacrylated Carboxymethyl Chitosan (CMChMA)

Methacrylated Carboxymethyl Chitosan (CMChMA)

Methacrylated Carboxymethyl Chitosan (CMChMA) is a photocrosslinkable derivative of carboxymethyl chitosan, a highly water‑soluble biopolymer known for its excellent biocompatibility, biodegradability, hemostatic activity, and antimicrobial properties. By introducing methacryloyl groups, CMChMA combines the natural bioactivity and calcium‑binding capability of carboxymethyl chitosan with rapid light‑induced hydrogel formation, enabling precise spatiotemporal control of crosslinking. This versatile material is widely used in tissue engineering, wound healing, dental regeneration, drug delivery, gene carriers, and advanced biomanufacturing applications, offering strong potential for next‑generation regenerative medicine and photocurable hydrogel systems.
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Description

Carboxymethyl chitosan is a highly water‑soluble derivative of chitosan that retains the native biocompatibility, biodegradability, hemostatic properties, and antimicrobial activity of chitosan, while the introduction of carboxymethyl groups significantly enhances its solubility, film‑forming ability, sustained‑release behavior, and metal‑ion chelation capacity. Its zwitterionic nature and molecular structure confer strong affinity for calcium ions, enabling effective regulation of biomineralization processes. As a result, it shows great promise in bone tissue repair, dental regenerative medicine, and wet‑environment tissue engineering. In addition, carboxymethyl chitosan is widely used in wound healing, drug delivery, gene carriers, and bioimaging applications.

Our CMChMA is a photosensitive, methacrylated biopolymer obtained by introducing methacryloyl (MA) groups onto carboxymethyl chitosan. This material combines excellent biological activity with photocrosslinking processability, allowing rapid in situ hydrogel formation under photoinitiated conditions. The spatiotemporal controllability of its crosslinking behavior greatly expands its potential in biomanufacturing and regenerative medicine.

 

Product Features

  • Rapid Photocuring and Gel Formation Exhibits light‑responsive crosslinking capability, enabling second‑scale gelation and the fabrication of complex structures.
  • Excellent Biocompatibility and Functional Bioactivity The carboxymethyl chitosan backbone provides multiple biological functions, including hemostatic, antimicrobial, and pro‑regenerative activity.
  • Enhanced Water Solubility and Metal‑Chelation Capacity Carboxymethylation improves solubility and ion‑binding properties, expanding its applicability across diverse biological environments.
  • Flexible Composite Crosslinking Can be combined with other photocurable biopolymers to tailor hydrogel performance for specific applications.

 

Product Advantages

  • High Batch‑to‑Batch Stability Standardized manufacturing processes ensure consistent product performance and excellent experimental reproducibility.
  • High Purity with Low Residuals Purification procedures effectively remove small‑molecule impurities, ensuring biological safety.
  • Rigorous Quality Control Each batch undergoes multiple inspections to ensure compliance with research‑grade application requirements.
  • Flexible Customization Services Supports customized specifications, packaging options, and performance parameters to meet diverse needs.

 

MA Series

  • Methacrylated Carboxymethyl Cellulose (CMCMA)
  • Methacrylated Chondroitin Sulfate (CSMA)
  • Methacrylated Chitosan (ChMA)
  • Methacrylated Carboxymethyl Chitosan (CMChMA)
  • Tri‑Arm Poly(ε‑caprolactone) Methacrylate (3ArmPCLMA)
  • Methacrylated Gellan Gum (GGMA)
  • Methacrylated Hyaluronic Acid (HAMA)
  • Methacrylated Sericin (SerMA)
  • Methacrylated Sodium Alginate (AlgMA)
  • Methacrylated Polyvinyl Alcohol (PVAMA)
  • Gelatin Methacryloyl (GelMA)
  • Methacrylated Silk Fibroin (SilMA)

 

 

Only for research and not intended for treatment of humans or animals

 

 

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SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

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