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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.

from China, for the World

for Superior Biology Services since 2000

  • Products 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Natural Compounds
    • Enzymes
  • POCT 
    • 6 POCT Platforms
    • LAMP
    • RPA
    • CRISPR
    • Freeze-Drying System
    • Lateral Flow System
    • DNA-Free Enzymes
    • Pathogen Detection
  • Synbio 
    • Synthetic Biology
    • NMN
    • SBS Insights
  • About 
    • About SBS
    • Achievements
    • Ecosystem
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  • …  
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      • All Products
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      • Innovative Systems
      • Nucleic Acid Related
      • Natural Compounds
      • Enzymes
    • POCT 
      • 6 POCT Platforms
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      • RPA
      • CRISPR
      • Freeze-Drying System
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Methacrylated Gellan Gum (GGMA)

Methacrylated Gellan Gum (GGMA)

Methacrylated Gellan Gum (GGMA) is a photocrosslinkable derivative of gellan gum, an anionic microbial polysaccharide known for its strong thermoreversible gelation and ability to form hydrogels at low concentrations. By introducing methacryloyl groups, GGMA retains the natural temperature‑responsive behavior of gellan gum while gaining rapid light‑induced crosslinking capability under UV or visible light. Compared with traditional thermosensitive gellan gum gels, GGMA hydrogels exhibit significantly enhanced mechanical strength and structural stability. As a versatile biomaterial for 3D cell culture, tissue‑engineering scaffold fabrication, and bio‑3D printing, GGMA enables the construction of robust, customizable hydrogel systems for advanced biomedical and biofabrication applications.
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Description

Gellan gum is an anionic microbial polysaccharide composed of β‑1,3‑D‑glucose, β‑1,4‑D‑glucuronic acid, and α‑1,4‑L‑rhamnose in a molar ratio of 2:1:1. It exhibits pronounced thermoreversible gelation behavior, forming hydrogels at low concentrations (e.g., 1%). Below 35 °C, gellan gum adopts a double‑helix structure, while at elevated temperatures (above 70 °C) it transitions into a random‑coil conformation.

GGMA is obtained by introducing methacryloyl (MA) groups onto the gellan gum backbone. This modification preserves the natural thermosensitivity of gellan gum while adding photocrosslinking capability. In the presence of a photoinitiator, GGMA can be rapidly cured under UV or visible light to form hydrogels. Compared with traditional thermosensitive gellan gum gels, GGMA hydrogels exhibit significantly enhanced structural stability and mechanical strength, making them highly suitable for advanced applications such as 3D cell culture, tissue‑engineering scaffold fabrication, and bio‑3D printing.

 

Product Advantages

  • High Batch‑to‑Batch Consistency: Standardized manufacturing processes ensure reliable and consistent product performance across batches.
  • High Purity with Low Residuals: Purification procedures effectively remove small‑molecule impurities, ensuring biological safety.
  • Rigorous Quality Control System: Each batch undergoes multiple inspections to ensure compliance with research and development requirements.
  • Flexible Customization Services: Supports customized specifications and performance parameters, along with scalable production to meet diverse application needs.

 

MA Series

  • Methacrylated Carboxymethyl Cellulose (CMCMA)
  • Methacrylated Chondroitin Sulfate (CSMA)
  • Methacrylated Chitosan (ChMA)
  • Methacrylated Carboxymethyl Chitosan (CMChMA)
  • Tri‑Arm Poly(ε‑caprolactone) Methacrylate (3ArmPCLMA)
  • Methacrylated Gellan Gum (GGMA)
  • Methacrylated Hyaluronic Acid (HAMA)
  • Methacrylated Sericin (SerMA)
  • Methacrylated Sodium Alginate (AlgMA)
  • Methacrylated Polyvinyl Alcohol (PVAMA)
  • Gelatin Methacryloyl (GelMA)
  • Methacrylated Silk Fibroin (SilMA)

 

 

Only for research and not intended for treatment of humans or animals

 

 

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SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

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