
Polycaprolactone (PCL)
Description
Polycaprolactone (PCL) is a synthetic, biodegradable aliphatic polyester that ultimately degrades into non‑toxic byproducts such as water and carbon dioxide in vivo. As the first aliphatic polyester approved by the U.S. FDA for biomedical use, PCL has become a foundational material in tissue engineering and regenerative medicine. It features a low melting point, excellent processability, high flexibility, good extensibility, and outstanding biocompatibility and biodegradability, along with shape‑memory behavior that further broadens its application potential.
Thanks to these properties, PCL has been widely adopted across medical and industrial fields. In healthcare, it is used in bandages, drug‑delivery systems, bone graft substitutes, and a variety of tissue‑engineering scaffolds, including those for cartilage, bone, tendon, vascular, skin, and nerve regeneration. Its mechanical robustness, slow degradation rate, and compatibility with 3D printing and melt‑processing technologies make PCL an ideal candidate for long‑term implantable devices and structurally demanding biomedical applications.
Biomedical Research and Development Raw Materials
- Poly(lactic‑co‑glycolic acid) (PLGA)
- Polycaprolactone (PCL)
- Carboxymethyl Cellulose (CMC) | 9004‑32‑4
- Polyvinyl Alcohol (PVA) | 9002‑89‑5
- Gelatin | 9000‑70‑8
- Sodium Hyaluronate (HA) | 9067‑32‑7
- Sodium Alginate (Alg) | 9005-38-3
- F127 (Poloxamer 407) | 9003‑11‑6
Only for research and not intended for treatment of humans or animals

Journals Using SBS Genetech Products Universities Using SBS Genetech Products

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory








