Description

Gelatin is a partially hydrolyzed derivative of collagen, composed of linear polypeptide chains formed by crosslinked peptides and 18 amino acids. Its amino acid composition closely resembles that of native collagen, with glycine accounting for approximately one‑third of all residues—appearing at every third position along the chain. As the simplest amino acid, glycine imposes minimal steric hindrance and plays a key role in re‑forming helical structures during gelation. In contrast, imino acids such as proline and hydroxyproline (≈2/9 of total residues) contain pyrrolidine rings that restrict chain flexibility and contribute significantly to helix stabilization.

As a macromolecule derived from collagen, gelatin retains essential bioactive motifs, including the cell‑adhesive RGD sequence and matrix metalloproteinase (MMP)–sensitive sites. These features endow gelatin with excellent cell adhesion, enzymatic degradability, and biocompatibility, supporting cell attachment, proliferation, and differentiation. Owing to these biological advantages, gelatin has become a widely used biomaterial in tissue engineering, regenerative medicine, and 3D cell culture.

Product Information

Product Name: Gelatin 

CAS Number: 9000‑70‑8 

Storage Conditions: Store in a cool, dry place with the container tightly sealed.

Product Applications

• Gelatin Coatings and Capsule Formation: Gelatin exhibits excellent film‑forming ability, making it a widely used material for producing hard and soft pharmaceutical capsules. Its strong coating performance ensures uniformity, stability, and controlled dissolution, supporting a broad range of oral drug‑delivery applications.
• Plasma Substitute: Gelatin solutions possess osmotic pressure similar to human plasma albumin and demonstrate outstanding biocompatibility. These properties make gelatin an ideal raw material for plasma substitutes, where it helps maintain blood volume and circulatory stability in clinical settings.
• Hemostatic Sponges: Porous gelatin sponges are commonly used as hemostatic materials in surgical procedures. They rapidly absorb blood, promote clot formation at the injury site, and can be safely left in the body after surgery, where they are gradually degraded and absorbed.
• Cell Adhesion and Surface Coating: Gelatin provides strong cell‑adhesive properties due to its collagen‑derived bioactive motifs. It is frequently used to coat culture vessels, enhancing cell attachment and supporting the growth of adherent cell types in research and tissue‑engineering applications.

Biomedical Research and Development Raw Materials

• Poly(lactic‑co‑glycolic acid) (PLGA)
• Polycaprolactone (PCL)
• Carboxymethyl Cellulose (CMC) | 9004‑32‑4
• Polyvinyl Alcohol (PVA) | 9002‑89‑5
• Gelatin | 9000‑70‑8
• Sodium Hyaluronate (HA) | 9067‑32‑7
• Sodium Alginate (Alg) | 9005-38-3
• F127 (Poloxamer 407) | 9003‑11‑6 

Only for research and not intended for treatment of humans or animals

Journals Using SBS Genetech Products                                        Universities Using SBS Genetech Products

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory