
Poly(lactic‑co‑glycolic acid) (PLGA)
Description
Poly(lactic‑co‑glycolic acid) (PLGA) is a biodegradable copolymer synthesized from lactic acid (LA) and glycolic acid (GA). It is designed to combine the advantages of its two parent polymers—PLA and PGA—while overcoming their individual limitations. PLA offers good mechanical strength but suffers from poor hydrophilicity and slow degradation, whereas PGA degrades rapidly under mild conditions but is difficult to process and lacks toughness. By adjusting the LA/GA monomer ratio during copolymerization, PLGA enables precise control over mechanical properties and degradation kinetics. Commercial PLGA grades are typically defined by their LA/GA ratios, such as PLGA 85/15, 75/25, 65/35, and 50/50, where PLGA 75/25 indicates a 75%:25% LA‑to‑GA composition.
As a biocompatible, non‑toxic, and highly processable polymer with excellent film‑forming ability, PLGA has become one of the most important biodegradable materials in pharmaceuticals, biomedical engineering, and modern industrial applications. It is widely used in drug‑delivery systems (including sustained‑release and controlled‑release formulations), tissue‑engineering scaffolds, surgical sutures, regenerative implants, and other medical devices where tunable degradation and mechanical performance are essential.
Biomedical Research and Development Raw Materials
- Poly(lactic‑co‑glycolic acid) (PLGA)
- Polycaprolactone (PCL)
- Carboxymethyl Cellulose (CMC) | 9004‑32‑4
- Polyvinyl Alcohol (PVA) | 9002‑89‑5
- Gelatin | 9000‑70‑8
- Sodium Hyaluronate (HA) | 9067‑32‑7
- Sodium Alginate (Alg) | 9005-38-3
- F127 (Poloxamer 407) | 9003‑11‑6
Only for research and not intended for treatment of humans or animals

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