
Cellobiose 2‑Epimerase (CE)
Description
Cellobiose 2‑Epimerase (CE) is a specialized biocatalyst capable of converting β‑1,4‑linked disaccharides through a selective C‑2 epimerization reaction. It is widely studied for its ability to transform lactose into lactulose, offering a clean‑label and enzyme‑based alternative to traditional chemical isomerization methods. As demand for functional sugars continues to grow, CE has become an important enzyme in research, food innovation, and specialty carbohydrate development.
What Is Cellobiose 2‑Epimerase?
Cellobiose 2‑Epimerase is an epimerase enzyme originally identified in thermophilic and anaerobic microorganisms. It catalyzes the structural rearrangement of β‑1,4 disaccharides by altering the stereochemistry at the C‑2 position. This unique catalytic capability makes CE valuable for producing functional sugars, prebiotic ingredients, and specialty carbohydrate derivatives.
Key Benefits of Cellobiose 2‑Epimerase
Selective C‑2 epimerization of β‑1,4 disaccharides
Enzyme‑based alternative to chemical isomerization
Clean‑label and environmentally friendly bioprocessing
Applicable to lactose‑to‑lactulose conversion
Suitable for food, nutrition, and specialty carbohydrate development
Compatible with enzymatic production lines and bioprocess systems
These advantages make CE a promising tool for companies exploring new functional sugars and advanced carbohydrate technologies.
Applications of Cellobiose 2‑Epimerase
1. Lactulose Formation
CE is widely studied for its ability to convert lactose into lactulose under mild, food‑grade conditions. This provides a biological route for producing lactulose, a functional disaccharide used in digestive health, medical nutrition, and specialty food formulations.
2. Functional Sugar Development
CE supports the creation of novel β‑1,4 disaccharide derivatives with potential applications in:
Prebiotic ingredients
Gut‑health formulations
Low‑glycemic sweeteners
Specialty carbohydrate research
3. Bioprocess and Enzyme Engineering
CE is frequently used in:
Enzyme engineering studies
Biocatalytic pathway development
Thermophilic enzyme research
Novel carbohydrate synthesis
Its unique catalytic mechanism makes it a valuable model enzyme for academic and industrial R&D.
Why Choose Our Cellobiose 2‑Epimerase
Our CE is designed for manufacturers and research teams seeking:
Reliable performance in enzymatic conversion systems
Strong compatibility with lactose‑based substrates
Smooth integration into food‑grade or research‑grade workflows
Consistent quality for commercial and scientific applications
We also provide custom enzyme development, process optimization, and technical collaboration to support advanced carbohydrate innovation.
Related:
SBS Genetech is recognized as one of the global major leading industry players in Synthetic Biology by third-party market researchers. For more details, please visit Outlook on the Synthetic Biology: DNA Cloning Global Market to 2035 - Industry Trends and Forecasts.










