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      RNA-Related

      At SBS Genetech, we are at the forefront of offering comprehensive RNA-related products, ensuring robust DNA-RNA conversion

    • What is Ribonucleic Acid (abbreviated as RNA)?

      A Ribonucleotide Molecule

      Consists of phosphate, ribose and base

      Genetic Information Carrier

      Existing in biological cells, some viruses and viroids

      A Chain-Like Molecule

      Condensed by ribonucleotides via phosphodiester bonds

      Four Bases

      A (adenine), G (guanine), C (cytosine) and U (uracil)

    • DNA-RNA Conversion​

      Transcription of DNA to RNA

      A strand of DNA is used as a template for synthesizing a strand of RNA by RNA polymerase (e.g. T7 Thermostable RNA Polymerase). During this process, RNA polymerase binds to a site called the promoter and starts copying the nucleotides, where deoxyribonucleotides are replaced by ribonucleotides.

      Reverse Transcription of RNA to DNA

      Complementary DNA (cDNA) is generated from an RNA template by reverse transcriptase (e.g. Ultra Thermo-stable M-MLV Reverse Transcriptase). During this process, RNasin is usually used to prevent the degradation of RNA template.

    • T7 Thermostable RNA Polymerase

      Premium Solution for DNA to RNA Conversion

      Compared with wild-type phage T7 RNA polymerase, T7 Thermostable RNA polymerase can transcribe in vitro at higher temperature. It can efficiently transcribe in vitro at 37-52°C. The optimal temperature is 37°C. It still retains more than 50% of its activity at 50°C, while the wild type has no activity at this temperature. Based on this heat-resistant in vitro transcription reaction characteristics, it has the following advantages......

      Ultra Thermo-stable M-MLV Reverse Transcriptase

      Premium Solution for RNA to DNA Conversion

      Ultra Thermo-stable M-MLV Reverse Transcriptase (RNase H-) is a mutant type of M-MLV Reverse Transcriptase, obtained by eliminating the active center of RNase H through multiple point mutations. The alteration decreases activity of RNase H and reduces RNA degradation in reverse transcription, which increases the yield of first-strand cDNA to get full length cDNA more easily. In addition, thermal stability of the reverse transcriptase is improved and the enzyme is active up to 65°C. Compared with RT-PCR at low temperature, RT-PCR at high temperature can......

      RNasin (RNase Inhibitors)

      Premium Solution for RNA Template Protection

      RNasin is a ribonuclease inhibitor extracted from human placenta with a molecular weight 51 kDa. It inhibits the activity of RNase by specifically binding up to RNase with a non-covalent bond. RNasin, free of RNase or Nickase, can maintain its activity at pH from 5 to 8, with the highest activity at pH 7.8. The concentration of RNasin is 20~40 units/µl.

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    • RNA-Related​ Products

      PrimeRT™ First Strand cDNA Synthesis Premix (with gDNA Clean)
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      PrimeRT™ First Strand cDNA Synthesis Premix (with gDNA Clean)
      135.00 - 810.00
      PrimeRT™ First Strand cDNA Synthesis Premix
      Buy now
      PrimeRT™ First Strand cDNA Synthesis Premix
      135.00 - 810.00

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