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Cat. No.: HMGH-50 (for 50μg)

Cat. No.: HMGH-100 (for 100μg)

Cat. No.: HMGH-500 (for 500μg)

Description

Myoglobin (symbol Mb or MB) is an iron- and oxygen-binding protein found in the cardiac and skeletal muscle tissue of vertebrates, including nearly all mammals. It is distantly related to hemoglobin but differs in that it has a higher affinity for oxygen and does not exhibit cooperative binding with oxygen as hemoglobin does. In humans, myoglobin is present in the bloodstream only after muscle injury, making it a sensitive marker for such injuries. This sensitivity allows myoglobin to be a potential marker for heart attacks in patients with chest pain. However, elevated myoglobin levels have low specificity for acute myocardial infarction (AMI). Therefore, CK-MB, cardiac troponin, ECG, and clinical signs should also be considered for an accurate diagnosis.

Species

Human

Molecular Alias

symbol Mb, MB

Accession

P02144

Expression Sequence

Protein sequence (P02144, Met1-Gly154 with C-10*His)

MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQGGGGGSHHHHHHHHHH

Expression Host

E.coli

Molecular Weight

Theoretical: 18.8kDa 

Actual: 20kDa

Purity

95% by SDS-PAGE

Label

Unconjugated

Tag

His Tag

Form

Liquid

Storage Conditions

12 months from the date of receipt at -20°C as supplied.