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Cat. No.: HHF3H-50 (for 50μg)

Cat. No.: HHF3H-100 (for 100μg)

Cat. No.: HHF3H-500 (for 500μg)

Description

Heart-type fatty acid-binding protein (hFABP), also known as mammary-derived growth inhibitor, is encoded by the FABP3 gene in humans. H-FABP is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. It serves as a sensitive biomarker for myocardial infarction, detectable in the blood within one to three hours of the onset of chest pain. Beyond its diagnostic utility, H-FABP holds significant prognostic value. Among various cardiac biomarkers, including D-dimer, NT-proBNP, and peak troponin T, H-FABP stands out as a statistically significant predictor of death or myocardial infarction within one year. This prognostic capability is independent of troponin T levels, ECG findings, and clinical examinations.

Species

Human

Molecular Alias

Fatty acid-binding protein 3, Heart-type fatty acid-binding protein (H-FABP), Mammary-derived growth inhibitor (MDGI), Muscle fatty acid-binding protein (M-FABP)

Accession

P05413

Expression Sequence

Protein sequence(P05413, Met1-Ala133 with C-10*His)

MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEAGGGGSHHHHHHHHHH

Expression Host

E.coli

Molecular Weight

Theoretical: 16.5kDa 

Actual: 18kDa

Purity

95% by SDS-PAGE

Endotoxin content

<1 EU/μg

Label

Unconjugated

Tag

His Tag

Form

Lyophilized Powder

Reconstitution Method

Reconstitute at no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Storage Conditions

12 months from the date of receipt, at -20 to -70 °C as supplied.

1 month, at 2 to 8 °C under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.