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Cat. No.: HS1A8H-25 (for 25μg)

Cat. No.: HS1A8H-50 (for 50μg)

Cat. No.: HS1A8H-100 (for 100μg)

Description

S100A8 is a member of the S100 family of proteins, characterized by two EF-hand calcium-binding motifs. These proteins are found in the cytoplasm and/or nucleus of a diverse range of cells and play a role in regulating various cellular processes, including cell cycle progression and differentiation. The S100 gene family consists of at least 13 members clustered on chromosome 1q21. S100A8 may function in inhibiting casein kinase and acting as a cytokine. Altered expression of S100A8 has been linked to diseases such as cystic fibrosis and post-COVID-19 condition.

Species

Human

Molecular Alias

Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen (CFAG); Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8 (MRP-8; p8); Urinary stone protein band A; CAGA

Accession

P05109

Expression Sequence

Protein sequence(P05109, Met1-Glu93, with C-10*His)

MLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKEGGGGSHHHHHHHHHH

Expression Host

E.coli

Molecular Weight

Predicted MW: 12.5 kDa 

Observed MW: 13.0 kDa

Purity

＞95% by SDS-PAGE

Endotoxin content

<1 EU/μg

Tag

His Tag

Form

Lyophilized Powder

Buffer System

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

Reconstitution Method

Reconstitute at no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Storage Conditions

12 months from the date of receipt when stored at -20 to -70 °C as supplied.

6 months at -20 to -70 °C under sterile conditions after reconstitution.

1 week at 2 to 8 °C under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.