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Custom Services
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Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
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tech@sbsbio.com
from China, for the World
for
S
uperior
B
iology
S
ervices since
2000
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
…
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
Login
Freeze-Drying System - SBS Genetech - for Superior Biology Services since 2000
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Antibody
Biochemicals
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DNA-Free Enzymes
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Glycobiology
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IVD Bulk Reagents
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Magnetic Beads
Microspheres
Natural Compounds
Next Generation Sequencing
Nuclease
Nucleic Acid Purification
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PCR-Related
Peptide-Related
Protein-Related
Quick-Dissolve Pellets
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RNA-Related
RNA Silencing
RUO Kits
Sequencing
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Synthetic Biology
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dCas9 NLS (Lyophilized)
dCas9 NLS is a nuclease with a Nuclear Localization Signal (NLS) that specifically binds double-stranded DNA under the guidance of gRNA without cutting it. dCas9 NLS is a D10A/H840A double mutant created by amino acid mutations in the RuvC and HNH domains of the Cas9 nuclease. Like the wild-type Cas9 nuclease, dCas9 NLS targets the DNA sequence with the help of gRNA. However, due to mutations in the RuvC and HNH domains, dCas9 NLS has gRNA-guided DNA binding activity without endonuclease activity. Studies have shown that when dCas9 NLS is combined with proteins of different functions, it can effectively inhibit or promote gene expression. At the same time, dCas9 NLS provides a platform for these proteins to bind to specific genomic sites. This lyophilized format enables convenient room‑temperature shipping.
$240.00 - $1,280.00
$1,600.00
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EiCsm6 (Lyophilized)
CRISPR-Type Effector Nuclease Csm6: When activated by cyclic adenylation molecules or linear adenine homopolymers with 2',3'-cyclic phosphates at the ends, the trans-cleavage activity of LwaCas13a or PsmCas13b produces cleavage products with hydroxylated 5' ends and products with 2',3'-cyclic phosphate ends, which can activate Csm6. Csm6 can cleave the Reporter with polyA. This lyophilized format enables convenient room‑temperature shipping.
$1,386.00 - $3,850.00
$5,500.00
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LwaCas13a Nuclease (Lyophilized)
LwaCas13a (also known as C2c2) is a crRNA-guided RNA endonuclease dependent on crRNA alone, originating from the Leptotrichia wadei strain. It can specifically recognize and cleave target single-stranded RNA, with relatively lenient requirements for the PFS sequence. Additionally, Cas13a exhibits trans-cleavage activity (i.e., collateral cleavage activity). Upon formation of a ternary complex comprising LwaCas13a protein, crRNA, and target RNA, the enzyme is activated to cleave non-specific sequences of single-stranded RNA in the system, breaking down any sequence of single-stranded RNA. This activity has also been utilized in the development of rapid detection kits for target nucleic acids. This lyophilized format enables convenient room‑temperature shipping.
$350.00 - $1,610.00
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BrCas12a Nuclease (Lyophilized)
When guided by RNA, Cas12b recognizes and cleaves the target DNA, activating its "collateral cleavage" activity, efficiently cleaving nonspecific DNA in the system. By designing Reporter DNA labeled with fluorescent groups or other markers at both ends, CRISPR/Cas12b can detect and amplify signals of DNA templates. The results can then be observed using a fluorometer or test paper. It is characterized by its tolerance to high temperatures of 65°C and can be used in conjunction with LAMP isothermal amplification. This lyophilized format enables convenient room‑temperature shipping.
$771.00 - $4,950.00
$5,500.00
Buy now
AsCas12a Nuclease (Lyophilized)
AsCas12a (Cpf1), a novel tool for gene detection and imaging, has a similar function as Cas9 with a smaller size. This lyophilized format enables convenient room‑temperature shipping.
$308.00 - $1,463.00
$2,090.00
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