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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.
broken image

from China, for the World

for Superior Biology Services since 2000

  • Home
  • Product 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Natural Compounds
    • Synthetic Biology
    • Enzymes
  • POCT Solution 
    • LAMP
    • RPA
    • CRISPR
    • DNA-Free Enzymes
    • Freeze-Drying System
    • Lateral Flow System
  • About 
    • About SBS
    • Achievements
    • Ecosystem
    • Legal Statement
  • Contact
  • …  
    • Home
    • Product 
      • All Products
      • Custom Services
      • Catalog Products
      • Innovative Systems
      • Nucleic Acid Related
      • Natural Compounds
      • Synthetic Biology
      • Enzymes
    • POCT Solution 
      • LAMP
      • RPA
      • CRISPR
      • DNA-Free Enzymes
      • Freeze-Drying System
      • Lateral Flow System
    • About 
      • About SBS
      • Achievements
      • Ecosystem
      • Legal Statement
    • Contact
  • 0
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Beijing SBS Genetech Co.,Ltd.
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Methylation

Methylation

Methylation is an important modification of nucleic acid, which regulates the expression of genes. It is closely related to many diseases such as cancer, aging and Alzheimer's disease. It is one of the important research contents of epigenetics.
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DNA methylation is one of the earliest discovered epigenetic regulation mechanisms and is also one of the most deeply studied epigenetic regulation mechanisms. In a broad sense, DNA methylation refers to the chemical modification process in which a specific base on the DNA sequence obtains a methyl group by covalent bonding with S-adenosyl methionine (SAM) as a methyl donor under the catalysis of DNA methyltransferase (DNMT). 

Methylation is one of the important research contents of epigenetics. It is closely related to many following events:

  • Reprogramming: DNA methylation is an epigenetic process. Unlike DNA sequences inherited directly from parents, methylation patterns extracted from gametes are deleted before embryo implantation, and a new methylation map will be established for each individual.
  • Aging: methylation events occur in a highly specific manner during development, simulating the expression pattern of differentiated tissues. Whether methylation changes will affect the aging process needs further study.
  • Diseases: DNA methylation also plays a role in several human diseases.
  • Environment: Environmental factors affect DNA methylation status and may affect long-term gene expression patterns.
  • Diagnosis of human diseases: An emerging and exciting clinical application of DNA methylation is in the field of diagnosis.

At SBS Genetech, we can provide DNA methylation, RNA methylation and related research products. The main products are as follows:

  • 6m-dA
  • 5m-dC
  • 6m-rA
  • 5m-rC
  • 5m-rU

 

 
Only for research and not intended for treatment of humans or animals
 
 

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

 

 

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

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