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Cat. No.: HGV-2

Comparative sensitivity test of GV and EB

1. Sensitivity test of GoodView^TM Nucleic Acid Stain
   • Template：5～70 ng λDNA（λDNA diluted to different concentrations）
   • GoodView：add 5 μl GoodView to 100 ml 1% agarose gel solution.
2. Sensitivity test of EB
   • Template：5～70 ng λDNA（λDNA diluted to different concentrations）
   • EB：add 5 μl EB (10 mg/ml) to 100 ml 1% agarose gel solution, to make the final concentration to 0.5 ng/μl.

The result of electrophoresis demonstrates GV is almost as sensitive as EB.

Conclusion:

1. When comparing Fig.1 and Fig.2, it is clearly demonstrated that GoodView^TM has a much better sensitivity than product A.
2. The difference between Fig.3 and Fig.4 illustrates that although product B has a good sensitivity and a low background, it has shortage: apparently the ladder cannot be distinctively separated.

The Test Report from Environmental Health and Related Product Safety of Chinese Center for Disease Control and Prevention concludes that:

• Acute Oral Toxicity Test: GoodView^TM Nucleic Acid Stain belongs to nontoxic.
• Mouse Marrow Chromophilous Erythrocyte Micronucleus Test: Negative. There is no significant difference in the incidence of micronuclei between test and control groups.
• Ames Test: Negative. No mutagenicity was observed.
• In Vitro Mammalian Cell Chromosome Aberration Test: Negative. No increasing aberration rate was observed.

Instruction: Protocol

GoodView™ Nucleic Acid Stain is included in New Products, Science Journal, January 11, 2019. Please visit: http://science.sciencemag.org/content/363/6423/193 

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