Comparative sensitivity test of GV and EB

Sensitivity test of GoodView^TM Nucleic Acid Stain
- Template：5～70 ng λDNA（λDNA diluted to different concentrations）
- GoodView：add 5 μl GoodView to 100 ml 1% agarose gel solution.
Sensitivity test of EB
- Template：5～70 ng λDNA（λDNA diluted to different concentrations）
- EB：add 5 μl EB (10 mg/ml) to 100 ml 1% agarose gel solution, to make the final concentration to 0.5 ng/μl.

The result of electrophoresis demonstrates GV is almost as sensitive as EB.

Conclusion:

When comparing Fig.1 and Fig.2, it is clearly demonstrated that GoodView^TM has a much better sensitivity than product A.
The difference between Fig.3 and Fig.4 illustrates that although product B has a good sensitivity and a low background, it has shortage: apparently the ladder cannot be distinctively separated.

Acute Oral Toxicity Test: GoodView^TM Nucleic Acid Stain belongs to nontoxic.
Mouse Marrow Chromophilous Erythrocyte Micronucleus Test: Negative. There is no significant difference in the incidence of micronuclei between test and control groups.
Ames Test: Negative. No mutagenicity was observed.
In Vitro Mammalian Cell Chromosome Aberration Test: Negative. No increasing aberration rate was observed.

GoodView™ Nucleic Acid Stain is included on New Products, Science Magazine, January 11, 2019. Please visit: http://science.sciencemag.org/content/363/6423/193