Description

Liquid-phase hybridization capture is a commonly used enrichment technique in targeted sequencing, where probes designed for the target regions are used to capture and enrich the desired sequences based on the principle of complementary base pairing. The core material for this technique is the capture probes, with DNA and RNA probes available in the market, each offering advantages suitable for different application scenarios. For smaller capture regions or fixed-site commercial catalog panels, DNA capture probes are an ideal choice. The quality and cost of the probes are important factors to consider in the application of liquid-phase hybridization capture technology in molecular diagnostics.

With the use of high-throughput DNA independent synthesis technology, we are able to individually synthesize and recover each sequence with astounding efficiency, while controlling the synthesis yield at the pmol level. Compared to traditional column-based synthesis, this technology offers significant advantages, including raw material savings, cost reduction, and better suitability for downstream applications. Our innovative approach will provide you with outstanding performance and economic benefits, helping you gain a competitive edge in the market.

Advantages

• High value for your investment through technological innovation: We utilize high-throughput DNA-independent synthesis technology to ensure synthesis quality and control synthesis yield at the picomole level, perfectly catering to a wide range of downstream application needs. This technological innovation reduces costs and provides outstanding value for our customers. Additionally, our innovative nucleic acid chemistry methods deliver probes with higher purity, ensuring the accuracy and reliability of your experiments.
• Stringent quality control for superior quality: We implement rigorous quality control measures, including independent normalization steps to ensure batch consistency. Independent recovery of each sequence ensures controlled quality. Furthermore, we perform dual quality control through mass spectrometry and NGS sequencing to ensure the stability and reliability of our provided products.
• Dedicated team serving your needs: Our experienced professional team is dedicated to efficiently meeting your demands with rapid synthesis cycles. As a raw material supplier, we commit to protecting the confidentiality of your sequences and ensuring the security of your research projects. Additionally, we offer high-quality complementary reagents such as closure fluids, hybridization liquids, and adapters to meet the comprehensive requirements of your experiments.