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tech@sbsbio.com
Beijing SBS Genetech Co.,Ltd.
Beijing SBS Genetech Co.,Ltd.
broken image

from China, for the World

for Superior Biology Services since 2000

  • Home
  • Product 
    • All Products
    • Custom Services
    • Catalog Products
    • Innovative Systems
    • Nucleic Acid Related
    • Natural Compounds
    • Synthetic Biology
    • Enzymes
  • POCT Solution 
    • LAMP
    • RPA
    • CRISPR
    • DNA-Free Enzymes
    • Freeze-Drying System
    • Lateral Flow System
  • About 
    • About SBS
    • Achievements
    • Ecosystem
    • Legal Statement
  • Contact
  • …  
    • Home
    • Product 
      • All Products
      • Custom Services
      • Catalog Products
      • Innovative Systems
      • Nucleic Acid Related
      • Natural Compounds
      • Synthetic Biology
      • Enzymes
    • POCT Solution 
      • LAMP
      • RPA
      • CRISPR
      • DNA-Free Enzymes
      • Freeze-Drying System
      • Lateral Flow System
    • About 
      • About SBS
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Funcbeads™ Hydroxyl Oligo (dT) Magnetic Beads

Funcbeads™ Hydroxyl Oligo (dT) Magnetic Beads

Funcbeads™ Hydroxyl Oligo (dT) Magnetic Beads enable the isolation and extraction of mRNA from a wide range of samples. Due to the characteristics of magnetic beads, this process can be easily scaled up or down depending on the sample, improving flexibility for downstream applications.
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Description

Funcbeads™ Hydroxyl Oligo (dT) Magnetic Beads can be rapidly and completely separated when a magnetic field is present. Utilizing standard hybridization conditions, polyadenylated RNA (poly-A + RNA) can be easily bound onto the oligo (dT) set, and other RNAs (rRNA and tRNA) do not contain poly A+ sequences and therefore will not bind to oligo (dT) magnetic beads. Therefore, the isolated mRNA has high purity and can be used directly in downstream applications such as cloning and expression analysis.

 

Uniformity of particle size and composition

Tightly controlled production processes result in core-shell beads which are uniform and spherical. The silica shell provides a high content of silanol surface groups and encloses the magnetic core, as confirmed by Fourier-Transformed Infrared (FT-IR) spectroscopy. The submicron size allows for a high surface area and abundant binding sites. The narrow particle size distribution provides uniformity and consistency of the beads. The high zeta-potential values indicate a high surface charge, allowing for monodispersity and stable suspensions (long gravity settling time/low sedimentation rate) which contribute to ease of handling during use. As a result, VirusMag™ Magnetic Beads delivers a high-performance surface and regular morphology to optimize binding efficiency and reduce variability.

 

Principle

An appropriate lysis buffer is first added to the sample, followed by incubation with beads. The beads with bound DNA/RNA are easily pulled to the side of the test tube by applying a magnetic field, and unbound material is removed by aspiration. The magnetic separation also facilitates simple washing and elution of the isolated nucleic acids. The protocol and buffer systems used should be optimized relative to your specific sample type and target material.

 

Storage

Minimum shelf life in one year at 2-8°C.

 

Related: Funcbeads™ Hydroxyl Magnetic Beads​, Funcbeads™ Amino Magnetic Beads, Funcbeads™ SA Magnetic Beads, Funcbeads™ Carboxyl Magnetic Beads, Funcbeads™ Anti-FLAG Magnetic Beads

 

 

Only for research and not intended for treatment of humans or animals

 

 

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

 

 

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory

 

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