for Superior Biology Services
for Superior Biology Services
A fast, accurate and convenient biological nucleic acid detection solution
BodyIAmp™ is an innovative enzymatic isothermal amplification technology that uses advanced molecular design, directed evolution, affinity maturation, and other technologies in the field of antibody pharmaceuticals to transform and optimize the molecular structure and function of DNA polymerase, endonuclease, and other tool enzymes from bacteria, viruses, and bacteriophages.
The modified DNA tool enzyme is combined with the primer to form a protein-DNA complex. The homologous sequence is found in the double-stranded DNA and DNA synthesis is started. The target gene on the template is expanded exponentially. This technology has high sensitivity and specificity, reduces the generation of mismatch, and thus reduces the probability of test error.
BodyIAmp™ technology can amplify the specific segment of trace target DNA/RNA by hundreds of millions of times in 7-10 minutes under body temperature (37°C-42°C) conditions. Its low-temperature adaptability and sensitivity have made major breakthroughs and reached the international advanced level.
In most cases, trace nucleic acid samples can be amplified to detectable levels in 7-10 minutes.
The detection limit can reach 10-100 copies/reaction.
The reaction and detection are conducted in a closed tube to avoid aerosol pollution.
The optimum temperature is 37°C-42°C constant temperature, which reduces the requirements for equipment and has wide equipment versatility.
The product is freeze-dried and can be transported at room temperature. It can be stored at -20°C for more than one year.
The main components of the product are prefabricated into microspheres by an advanced freeze-drying process, without the need for professional equipment and training.
What is the principle of BodyIAmp™?
What is the difference between BodyIAmp™ and RPA?
Can the amplification products be used for SHERLOCK or DETECTR experiments?
Representative Publications Using SBS Genetech Isothermal Amplification Products
Xue, T. , Ma, Z. , Liu, F. , Du, W. , & An, C. . (2020). Pneumocystis jirovecii colonization and its association with pulmonary diseases: a multicenter study based on a modified loop-mediated isothermal amplification assay. BMC Pulmonary Medicine, 20(1).
Zhao, K. , Hu, R. , Ni, J. , Liang, J. , & Li, C. . (2020). Establishment of a porcine parvovirus (PPV) LAMP visual rapid detection method. Journal of Virological Methods, 284, 113924.
Papadakis, G. , Pantazis, A. K. , Fikas, N. , Chatziioannidou, S. , Tsiakalou, V. , & Michaelidou, K. , et al. (2022). Portable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples. Scientific Reports, 12(1), 1-15.
Wu, R. , Liu, X. , Guo, B. , Chen, F. , & Wang, X. . (2014). Development of double loop-mediated isothermal amplification to detect listeria monocytogenes in food. Current Microbiology, 69(6), 839-845.
Ji, J. , Du, L. Q. , Xie, Q. M. , Cao, Y. C. , & Bee, Y. Z. . (2009). Rapid diagnosis of duck plagues virus infection by loop-mediated isothermal amplification. Research in Veterinary Science, 87(1), 53-58.
Zhang, S. , Xu, X. , Wu, Q. , & Zhang, J. . (2013). Rapid and sensitive detection of pseudomonas aeruginosain bottled water by loop-mediated isothermal amplification. European Food Research & Technology, 236(1), 209-215.
Xu, X. , Zhang, S. , Wu, Q. , Zhang, J. , Li, F. , & Cheng, J. . (2014). Development and Application of a Loop-Mediated Isothermal Amplification (LAMP) Method for Rapid and Sensitive Detection of Enterococcus faecalis in Drinking Water. Journal of Food Safety, 34(2), 103–110.
Zhang, F. , Shi, Y. , Jiang, K. , Song, W. , Ma, C. , & Xu, Z. , et al. (2014). Rapid detection and quantification of Prorocentrum minimum by loop-mediated isothermal amplification and real-time fluorescence quantitative PCR. Journal of Applied Phycology, 26(3), 1379-1388.
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