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Cat. No.: SDSG-1k (for 1000g) 

Description

Sodium dodecyl sulfate (SDS) is an organic compound that is soluble in water. It possesses degreasing, emulsifying, and excellent foaming properties and can be used for protein denaturation. It is a long-chain hydrocarbon group with negatively charged sulfate, making it a natural amphoteric surfactant. In DNA extraction processes, it helps separate proteins from DNA after denaturation and is commonly used in biochemical and immunological assays.

Conventional SDS is in powder form with small particle sizes, making it unable to be effectively filtered by regular dust masks. It can easily adhere to mucous membranes, the upper respiratory tract, eyes, and skin, causing irritation and potentially triggering allergic reactions in the respiratory system. However, the manufacturing process has been optimized to produce SDS as dust-free granules, which significantly reduces the potential harm to the human body caused by the powder.

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Components

• SDS dust-free Granules: 1000g

Application

• SDS is an anionic surfactant commonly used for the electrophoretic separation of proteins and lipids. When mixed with proteins at a mass ratio of 1.4:1, SDS disrupts non-covalent bonds between protein molecules and other substances, leading to a change in protein conformation and denaturation into individual subunits. This process reduces or eliminates natural charge differences between protein molecules. A common practice in electrophoresis is to use a 10% SDS solution as a stock solution.
• SDS can rapidly disrupt tissue structure and inhibit the activity of RNases and DNases. Therefore, SDS is also a crucial component in nucleic acid purification reagents. Typically, 10% or 20% SDS stock solutions are used, and the working concentration of SDS ranges from 0.1% to 0.5%.
  

Storage

Room temperature.

Only for research and not intended for treatment of humans or animals

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