
Schaftoside | 51938-32-0
$92.00 - $495.00
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Cat. No.: SCFS-0.2 (for 10mM×0.2ml)
Cat. No.: SCFS-5 (for 5mg)
Cat. No.: SCFS-25 (for 25mg)
Description
Schaftoside, a flavonoid found in various Chinese herbal medicines like Eleusine indica, exhibits inhibitory effects on the expression of TLR4 and Myd88. Additionally, it downregulates Drp1 expression and phosphorylation, thereby reducing mitochondrial fission.
Basic Information
- Aliases: -
- Source: Desmodium styracifolium (Osh.) Merr.
- Compound type: Flavonoids > Flavones
- Chemical Formula: C26H28O14
- Molecular Weight: 564.49
- CAS Number: 51938-32-0
- Purity: 98%, HPLC
- Solvent/Solubility: DMSO: 125 mg/ml (221.44 mM)
- Solution Preparation: 10mg can be dissolved in 1.77ml of DMSO, or alternatively, 5.64mg can be dissolved in 1ml of DMSO to prepare a 10mM solution.
Signaling Pathway
Inflammation |
In Vitro Study
Schaftoside effectively inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Additionally, it suppresses the mRNA and protein expressions of proinflammatory cytokines (IL-1β, TNF-α, and IL-6).
In Vivo Study
N/A |
Clinical Trial
N/A
Storage
Store at -20°C in the dark, stable for at least one year. Store solid powder at 4°C in the dark, stable for at least one month. If dissolved in a non-DMSO solvent, it is recommended to aliquot and store at -80°C in the dark, stable for an estimated six months.
Precautions
- This product may have a certain degree of toxicity to the human body. Please take appropriate precautions to avoid direct contact with the body or inhalation.
- This product is for scientific research use only by professionals and is not intended for clinical diagnosis or treatment, food, or pharmaceutical purposes. It should not be stored in ordinary residential areas.
- For your safety and health, please wear laboratory attire and disposable gloves while handling.
Only for research and not intended for treatment of humans or animals
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