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tech@sbsbio.com
from China, for the World
for
S
uperior
B
iology
S
ervices since
2000
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
…
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
Login
Nuclease - SBS Genetech - for Superior Biology Services since 2000
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Nucleic Acid Purification
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PCR-Related
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RUO Kits
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Synthetic Biology
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HheCas13a (C2c2)
HheCas13a is a crRNA‑guided RNA endonuclease derived from Herbinix hemicellulosilytica. Compared with commonly used Cas13a orthologs such as LwaCas13a and LbuCas13a, HheCas13a exhibits enhanced thermostability. In its RNP form, HheCas13a maintains strong catalytic activity across 37–60 °C, with an optimal reaction temperature of 52 °C. Guided by crRNA, HheCas13a specifically recognizes single‑stranded RNA (ssRNA) targets and does not strictly depend on a protospacer flanking site (PFS).
$650.00 - $3,140.00
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TccCas13a (C2c2)
TccCas13a is a crRNA‑guided RNA endonuclease derived from Thermoclostridium caenicola. Compared with commonly used Cas13a orthologs such as LwaCas13a and LbuCas13a, TccCas13a exhibits markedly enhanced thermostability. In its RNP form, TccCas13a maintains strong catalytic activity across 42–72 °C, with an optimal reaction temperature of 56–60 °C. Guided by crRNA, TccCas13a specifically recognizes single‑stranded RNA (ssRNA) targets and does not strictly depend on a protospacer flanking site (PFS).
$650.00 - $3,140.00
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YmeCas12a (Cpf1)
YmeCas12a is derived from a Yellowstone metagenome and is a thermostable, crRNA‑guided DNA endonuclease. It exhibits strong catalytic activity across a broad temperature range (37–60 °C), with an optimal reaction temperature of 56 °C. YmeCas12a preferentially recognizes the PAM sequence TTTV (V = A/C/G). For double‑stranded DNA (dsDNA) targets, efficient recognition and cleavage require the presence of a PAM site, whereas single‑stranded DNA (ssDNA) targets can be cleaved without PAM dependence.
$500.00 - $1,750.00
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CmeCas12a (Cpf1)
CmeCas12a is derived from a compost metagenome and is a thermostable, crRNA‑guided DNA endonuclease. It exhibits robust catalytic activity across a broad temperature range (37–56 °C), with an optimal reaction temperature of 52 °C. CmeCas12a preferentially recognizes the PAM sequence TTTV (V = A/C/G). For double‑stranded DNA (dsDNA) targets, efficient recognition and cleavage require the presence of a PAM site, whereas single‑stranded DNA (ssDNA) targets can be cleaved without PAM dependence.
$500.00 - $1,750.00
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RNase If
RNase If, also known as RNase I‑MBP, is a fusion protein consisting of E. coli RNase I and maltose‑binding protein (MBP), and it retains the same endoribonuclease activity as RNase I. RNase If recognizes and cleaves both single‑stranded RNA (ssRNA) and double‑stranded RNA (dsRNA), generating 5′‑hydroxyl termini and 2′,3′‑cyclic phosphate intermediates, which subsequently hydrolyze to form 3′‑monophosphate nucleotides. The enzymatic activity of RNase If does not require the presence of metal ions, and in the absence of calcium ions, RNase If degrades ssRNA more efficiently than dsRNA. Unlike RNase T1 and RNase A, the activity of RNase If is not inhibited by RNase inhibitor.
$164.00 - $629.00
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