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tech@sbsbio.com
from China, for the World
for
S
uperior
B
iology
S
ervices since
2000
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
Contact
…
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Natural Compounds
Enzymes
POCT
6 POCT Platforms
LAMP
RPA
CRISPR
Freeze-Drying System
Lateral Flow System
DNA-Free Enzymes
Pathogen Detection
Synbio
Synthetic Biology
NMN
SBS Insights
About
About SBS
Achievements
Ecosystem
Legal Statement
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All Categories - SBS Genetech - for Superior Biology Services since 2000
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TagmentX™ Fast DNA Library Prep Kit for MGI
The TagmentX™ Fast DNA Library Prep Kit for MGI is a purpose‑built solution designed specifically for Illumina high‑throughput sequencing platforms. This kit efficiently converts DNA samples into high‑quality libraries compatible with all MGI systems. Leveraging advanced transposase‑based technology, it integrates multiple traditionally separate steps—DNA fragmentation, end repair, and adapter ligation—into a single enzymatic reaction. This breakthrough not only dramatically reduces the amount of input DNA required but also significantly shortens the overall library preparation time.
$600.00 - $1,800.00
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TagmentX™ Fast DNA Library Prep Kit for Illumina
The TagmentX™ Fast DNA Library Prep Kit for Illumina is a purpose‑built solution designed specifically for Illumina high‑throughput sequencing platforms. This kit efficiently converts DNA samples into high‑quality libraries compatible with all Illumina systems. Leveraging advanced transposase‑based technology, it integrates multiple traditionally separate steps—DNA fragmentation, end repair, and adapter ligation—into a single enzymatic reaction. This breakthrough not only dramatically reduces the amount of input DNA required but also significantly shortens the overall library preparation time.
$600.00 - $1,800.00
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SaCas9
SaCas9 is a CRISPR nuclease derived from Staphylococcus aureus and is one of the most widely used compact Cas9 orthologs, offering distinct advantages for therapeutic genome editing. The protein consists of 1,053 amino acids with a molecular weight of approximately 120 kDa—about 25% smaller than SpCas9 (1,368 aa). This reduced size makes SaCas9 particularly well‑suited for delivery platforms with strict cargo limitations, such as AAV vectors.
$2,400.00 - $4,800.00
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MS2‑p65‑HSF1‑mCherry
MS2‑p65‑HSF1‑mCherry is a key auxiliary component of the Synergistic Activation Mediator (SAM) CRISPRa system. It builds upon the MS2‑p65‑HSF1 activation module by incorporating the red fluorescent protein mCherry, enabling simultaneous potent transcriptional activation and real‑time visualization.
$2,400.00 - $4,800.00
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dCas9‑GFP‑VP64
dCas9‑GFP‑VP64 is a multifunctional chimeric protein that integrates genomic targeting, real‑time visualization, and transcriptional activation. It consists of catalytically inactive Cas9 (dCas9), green fluorescent protein (GFP), and the VP64 transcriptional activation domain. The dCas9 component carries the D10A and N863A mutations, which completely abolish nuclease activity while preserving precise DNA‑binding capability directed by a single‑guide RNA (sgRNA).
$2,400.00 - $4,800.00
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OpenCRISPR‑1
OpenCRISPR‑1 is the world’s first gene editor designed entirely by artificial intelligence. The Profluent research team began by mining 26.2 terabases of microbial genomic data to construct the CRISPR‑Cas Atlas, a database containing more than 1.24 million CRISPR operons—over four times the Cas9 sequence diversity found in UniProt. Using this unprecedented dataset, the team fine‑tuned the protein language model ProGen2 to generate 4.8 million novel CRISPR‑associated protein sequences, from which OpenCRISPR‑1 emerged as the top‑performing candidate after rigorous screening and functional validation.
$2,400.00 - $4,800.00
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IscB (insertion sequences Cas9‑like OrfB)
IscB (insertion sequences Cas9‑like OrfB) is an RNA‑guided DNA nuclease encoded within the IS200/IS605 transposon family and is considered an evolutionary ancestor of the CRISPR‑Cas9 system. As a member of the OMEGA (Obligate Mobile Element‑Guided Activity) system family, its discovery provides key insights into the molecular evolution of CRISPR‑Cas systems.
$2,400.00 - $4,800.00
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dPspCas13b‑ADAT2
dPspCas13b‑ADAT2 is an RNA‑editing tool based on CRISPR technology and serves as a core component of the REPAIR (RNA Editing for Programmable A‑to‑I Replacement) system. This fusion protein combines catalytically inactivated Prevotella sp. P5‑125 Cas13b (dPspCas13b) with the adenosine deaminase ADAT2 domain, enabling precise base editing at the RNA level and offering a novel strategy for correcting pathogenic RNA mutations.
$2,400.00 - $4,800.00
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LtCas12a
LtCas12a is a thermophilic type V‑A CRISPR nuclease derived from Lachnospiraceae thermophila, representing a unique member of the Cas12a family with distinct thermostability advantages. The protein fully retains the hallmark biochemical features of Cas12a nucleases: recognition of a T‑rich PAM sequence (5'-TTTV-3'), sequential cleavage of double‑stranded DNA via a single RuvC nuclease domain, and generation of 5–7 nt 5' overhangs. LtCas12a also possesses intrinsic crRNA processing capability and exhibits trans‑cleavage activity upon target recognition.
$500.00 - $4,800.00
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TREX2‑FrCas9
TREX2‑FrCas9 is an engineered fusion protein combining FrCas9 with Three‑prime Repair Exonuclease 2 (TREX2), a 3'→5' exonuclease that profoundly alters the DNA repair outcomes of CRISPR‑Cas9 editing. TREX2 progressively digests nucleotides from DNA double‑strand break (DSB) ends, and when fused to FrCas9, it generates substantially larger deletions at the cleavage site.
$2,400.00 - $4,800.00
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eFrCas9
eFrCas9 is an engineered, enhanced version of FrCas9, developed through rational design based on cryo‑EM structural analysis of the FrCas9–sgRNA–DNA ternary complex combined with large‑scale mutational screening. By introducing targeted mutations into key residues within the phosphate lock loop and the PAM‑distal region, researchers significantly improved both the precision and efficiency of this Cas9 variant.
$500.00 - $4,800.00
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FrCas9
FrCas9 is a novel type II‑A CRISPR‑Cas9 nuclease derived from Faecalibaculum rodentium, adding an important new member to the genome‑editing toolbox. The protein consists of 1,372 amino acids and is distinguished by its unique palindromic PAM recognition sequence, 5'-NNTA-3'. This simple dinucleotide core PAM not only greatly expands the range of editable genomic sites but also confers a remarkable capability—direct targeting of TATA‑box elements in eukaryotic promoters.
$500.00 - $4,800.00
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PE2 (Prime Editor 2)
PE2 (Prime Editor 2) is the core component of the pioneering prime‑editing system, enabling precise genome modifications without introducing DNA double‑strand breaks. PE2 is a fusion protein composed of the SpCas9(H840A) nickase and an engineered Moloney murine leukemia virus reverse transcriptase (M‑MLV RT). The Cas9 module carries the H840A point mutation, which specifically inactivates the HNH nuclease domain while retaining RuvC activity. As a result, the enzyme introduces a single‑strand nick on the non‑complementary DNA strand under pegRNA guidance.
$2,400.00 - $4,800.00
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MS2‑p65‑HSF1
MS2‑p65‑HSF1 is a key auxiliary protein component of the Synergistic Activation Mediator (SAM) CRISPRa system, representing a major innovation in second‑generation CRISPR activation technologies. This fusion protein consists of three functional modules: the MS2 bacteriophage coat protein, the NF‑κB p65 transcriptional activation domain, and the heat shock factor 1 (HSF1) activation domain. The MS2 domain specifically recognizes and binds MS2 aptamer sequences embedded within RNA stem‑loop structures, while p65 and HSF1 provide strong transcriptional activation capacity.
$2,400.00 - $4,800.00
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dCas9‑VP64
dCas9‑VP64 is a synthetic fusion protein composed of nuclease‑dead Cas9 (dCas9) and the VP64 transcriptional activation domain, representing the core component of first‑generation CRISPR activation (CRISPRa) systems. The dCas9 module carries the D10A and N863A double mutations, which completely abolish DNA cleavage activity while preserving the ability to bind target DNA sequences with high precision under sgRNA guidance.
$2,400.00 - $4,800.00
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nCas9(D10A)-sfGFP
nCas9(D10A)-sfGFP is a fusion protein consisting of the SpCas9 nickase variant carrying the D10A point mutation and superfolder GFP (sfGFP). This design integrates precise single‑strand DNA cleavage capability with robust real‑time fluorescence visualization. The D10A mutation specifically inactivates the RuvC nuclease domain while preserving the catalytic activity of the HNH domain. As a result, the enzyme introduces a single‑strand nick exclusively on the DNA strand complementary to the sgRNA, rather than generating a double‑strand break as seen with wild‑type SpCas9.
$2,400.00 - $4,800.00
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SpCas9‑sfGFP
SpCas9‑sfGFP nuclease is a fusion protein combining Streptococcus pyogenes Cas9 (SpCas9) with superfolder GFP (sfGFP), integrating genome‑editing capability with robust fluorescence visualization. sfGFP is an engineered variant of traditional GFP, incorporating specific amino acid mutations that significantly enhance folding efficiency and structural stability. These improvements allow sfGFP to maintain strong fluorescence even when expressed as a fusion protein, overcoming the misfolding and fluorescence quenching issues commonly observed with wild‑type GFP.
$2,400.00 - $4,800.00
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Human Cot-1 DNA Pro (500 μg)
Human Cot‑1 DNA Pro is derived from genomic DNA extracted from human placenta. It consists of highly repetitive sequences approximately 50–300 bp in length. These repetitive elements effectively block repetitive regions present in probes or target nucleic acids, thereby preventing nonspecific hybridization signals during nucleic acid hybridization. By masking repetitive sequences, Human Cot‑1 DNA Pro enhances hybridization specificity and improves the efficiency of target sequence capture.
$400.00
$500.00
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Human Cot-1 DNA (500 μg)
Human Cot-1 DNA consists of highly repetitive sequences, approximately 50 to 300 base pairs in length, found within the human genome. It serves the purpose of conveniently and effectively blocking repetitive sequences within the nucleic acid sequences of probes or target samples. By blocking these repetitive sequences, it prevents interference from non-specific hybridization signals during the nucleic acid hybridization process. This enhancement of nucleic acid hybridization ultimately leads to the effective capture of nucleic acid sequences within the target nucleic acid sample, fulfilling its role as a "blocking" agent.
$280.00
$350.00
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Mouse Cot-1 DNA (500 μg)
Mouse Cot‑1 DNA is extracted from mouse liver and consists primarily of fragments ranging from 50 to 300 bp. It is highly enriched in repetitive DNA sequences, including members of the B1, B2, and L1 families. Mouse Cot‑1 DNA is commonly used to block nonspecific hybridization in microarray screening. It can also suppress hybridization of rodent repetitive sequences during in situ hybridization or Southern blot mapping of rodent clones, and it is useful for identifying mouse-derived clones in somatic cell hybrid library screening involving mouse–hamster hybrid cells.
$280.00
$350.00
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