Description

With pioneering technology and extensive experience in mRNA preparation, we offer comprehensive mRNA production services.

• High-Yield and Stable Capping Process: Achieves over 95% capping efficiency.
• Integrated PolyA Tail Transcription: Provides a more uniform distribution.
• Diverse mRNA Modifications: Modified nucleotides can effectively reduce adverse immune responses in the human body.
• Flexible Plasmid Template Design: Tailored to meet specific customer needs.

Services Provided

• Design and construction of mRNA template plasmids.

• Synthesis of standard mRNA (including Cap and PolyA).

• Synthesis of capped, tailed, and modified mRNA (e.g., ψ, N1-Me-Pseudo UTP).

• Diverse purification methods: Comprehensive purification solutions using tangential flow filtration and various chromatography resins effectively remove impurities from mRNA crude products, meeting high-quality application standards.

  • LiCl precipitation purification
  • Oligo dT magnetic bead purification
  • Chromatography column purification

• Comprehensive Quality Control Platform: Meets quality control needs at various research stages. Includes routine QC for research-grade concentrations and purity, as well as specialized QC for capping/PolyA tail efficiency and residue detection.

  • Sequence accuracy
  • Purity testing
  • Concentration testing
  • Capping efficiency testing
  • PolyA tail detection
  • Residue detection