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from China, for the World
for Superior Biology Services since 2000

Home
Products
All Products
Custom Services
Catalog Products
Innovative Systems
Nucleic Acid Related
Enzymes
POCT
Integrated POCT Platform
LAMP
RPA
CRISPR
DNA-Free Enzymes
Lateral Flow System
Freeze-Drying System
About
About SBS
Solutions
Achievements
Legal Statement
Contact
- Home
- Products
  All Products
  Custom Services
  Catalog Products
  Innovative Systems
  Nucleic Acid Related
  Enzymes
- POCT
  Integrated POCT Platform
  LAMP
  RPA
  CRISPR
  DNA-Free Enzymes
  Lateral Flow System
  Freeze-Drying System
- About
  About SBS
  Solutions
  Achievements
  Legal Statement
- Contact

- Login

pCMV-GCaMP6f (fast response calcium ion fluorescent probe)

pCMV-GCaMP6f (fast-response calcium ion fluorescence probe) is a mammalian cell expression plasmid for calcium ion (Ca2+) fluorescence detection. It has a fast response speed and is suitable for rapid calcium ion changes, high-frequency neural activity, and calcium ion imaging experiments that require higher time resolution. The pCMV-GCaMP6 series plasmids (GCaMP6s, GCaMP6m and GCaMP6f) are mammalian cell expression plasmids used for calcium ion (Ca2+) fluorescence detection. They express the M13-cpGFP-CaM fusion protein that has been mutated and optimized and suitable for calcium ion fluorescence detection in cells or tissues.

pCMV-GCaMP6m (moderate kinetics, high sensitivity calcium ion fluorescent probe)

pCMV-GCaMP6m (medium kinetics, high sensitivity calcium ion fluorescence probe) is a mammalian cell expression plasmid for calcium ion (Ca2+) fluorescence detection. It has balanced response kinetics and detection sensitivity. It is a classic universal calcium ion fluorescence probe and is suitable for calcium imaging experiments in most conventional cells and neurons. The pCMV-GCaMP6 series plasmids (GCaMP6s, GCaMP6m and GCaMP6f) are mammalian cell expression plasmids used for calcium ion (Ca2+) fluorescence detection. They express the M13-cpGFP-CaM fusion protein that has been mutated and optimized and suitable for calcium ion fluorescence detection in cells or tissues.

pCMV-GCaMP6s (highly sensitive calcium ion fluorescent probe)

pCMV-GCaMP6s (high-sensitivity calcium ion fluorescence probe) is a mammalian cell expression plasmid for calcium ion (Ca2+) fluorescence detection. It has high detection sensitivity and fluorescence response, and is suitable for detection of weak calcium signals and low-frequency neural activity. The pCMV-GCaMP6 series plasmids (GCaMP6s, GCaMP6m and GCaMP6f) are mammalian cell expression plasmids used for calcium ion (Ca2+) fluorescence detection. They express the M13-cpGFP-CaM fusion protein that has been mutated and optimized and suitable for calcium ion fluorescence detection in cells or tissues.

pCMV-Mito-AT1.03 (mitochondrial ATP fluorescent probe)

pCMV-Mito-AT1.03 (mitochondrial ATP fluorescent probe) contains a CMV promoter and is a tool plasmid for expressing the AT1.03 protein with a mitochondrial localization signal (MLS) in mammalian mitochondria as a fluorescent probe for cellular mitochondrial ATP. The ATP fluorescent probe expressed by this plasmid is called ATeam, which is an ATP indicator based on the ε subunit of FoF1-ATP synthase (Adenosine 5'-Triphosphate indicator based on Epsilon subunit for Analytical Measurements). AT1.03 is a low-affinity ATeam (Kd=3.3mM at 37℃) that can detect millimolar ATP levels.

pCMV-NLS-AT1.03 (nuclear ATP fluorescent probe)

pCMV-NLS-AT1.03 (nuclear ATP fluorescent probe) contains the CMV promoter and is a tool plasmid for expressing the AT1.03 protein with a nuclear localization signal (NLS) in the nucleus of mammalian cells as a nuclear ATP fluorescent probe. The ATP fluorescent probe expressed by this plasmid is called ATeam, which is an ATP indicator based on the ε subunit of FoF1-ATP synthase (Adenosine 5'-Triphosphate indicator based on Epsilon subunit for Analytical Measurements).

pCMV-AT1.03 (ATP fluorescent probe)

pCMV-AT1.03 (ATP fluorescent probe) is a tool plasmid containing the CMV promoter for expressing the AT1.03 protein in mammalian cells to serve as an ATP fluorescent probe. The ATP fluorescent probe expressed by this plasmid is known as ATeam, which stands for Adenosine 5'-Triphosphate indicator based on Epsilon subunit for Analytical Measurements, derived from the ε subunit of FoF₁-ATP synthase. AT1.03 is a low-affinity ATeam variant (Kd = 3.3 mM at 37 °C) capable of detecting ATP at the millimolar level. Following transfection into mammalian cells, the AT1.03 protein expressed from the pCMV-AT1.03 plasmid localizes predominantly in the cytoplasm, making it suitable for real-time monitoring of dynamic changes in cytoplasmic ATP concentration.

pCMV-dCas9-HDAC3

pCMV-dCas9-HDAC3 is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone deacetylation. This plasmid fuses and expresses dCas9 protein with histone deacetylase 3 (HDAC3). After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone acetylation control of single or multiple target genes can be achieved.

pCMV-dCas9-HDAC1

pCMV-dCas9-HDAC1 is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone deacetylation. This plasmid fuses and expresses dCas9 protein with histone deacetylase 1 (HDAC1). After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone acetylation control of single or multiple target genes can be achieved.

pCMV-dCas9-GCN5

pCMV-dCas9-GCN5 is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone acetylation modification. This plasmid fuses and expresses dCas9 protein with histone acetyltransferase GCN5. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone acetylation control of single or multiple target genes can be achieved.

pCMV-dCas9-P300

pCMV-dCas9-p300 is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone acetylation modification. This plasmid fuses and expresses dCas9 protein with histone acetyltransferase p300. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone acetylation control of single or multiple target genes can be achieved.

pCMV-dCas9-JMJD2A

pCMV-dCas9-JMJD2A is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone demethylation. This plasmid fuses and expresses dCas9 protein with lysine-specific demethylase 4A (JMJD2A). After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone methylation control of single or multiple target genes can be achieved.

pCMV-dCas9-LSD1

pCMV-dCas9-G9a

pCMV-dCas9-G9a is a plasmid that uses the CRISPR/dCas9 gene regulation system to perform histone methylation modification. This plasmid fuses and expresses dCas9 protein with histone H3K9 methyltransferase G9a. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone methylation control of single or multiple target genes can be achieved.

pCMV-dCas9-SET7/9

pCMV-dCas9-SET7/9 is a plasmid that uses the CRISPR/dCas9 gene regulation system to modify histone methylation. This plasmid fuses and expresses dCas9 protein with histone H3K4 methyltransferase SET7/9. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, the histone methylation regulation of single or multiple target genes can be achieved.

pCMV-dCas9-FTO

pCMV-dCas9-FTO is a plasmid that uses the CRISPR/dCas9 gene regulation system to carry out targeted RNA demethylation modification. This plasmid fuses and expresses dCas9 protein and m6A demethylase FTO. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, RNA methylation regulation of single or multiple target genes can be achieved.

pCMV-dCas9-ALKBH5

pCMV-dCas9-ALKBH5 is a plasmid that uses the CRISPR/dCas9 gene regulation system to carry out targeted RNA demethylation modification. This plasmid fuses and expresses dCas9 protein and m6A demethylase ALKBH5. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, RNA methylation regulation of single or multiple target genes can be achieved.

pCMV-dCas9-ALKBH5

pCMV-dCas9-ALKBH5 is a plasmid that uses the CRISPR/dCas9 gene regulation system to carry out targeted RNA demethylation modification. This plasmid fuses and expresses dCas9 protein and m6A demethylase ALKBH5. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, RNA methylation regulation of single or multiple target genes can be achieved.

pCMV-dCas9-M3-M14

The pCMV-dCas9-M3-M14 plasmid utilizes the CRISPR/dCas9 gene regulation system for targeted RNA methylation modification. This plasmid co-expresses the dCas9 protein with methyltransferase-like protein 3 (METTL3) and methyltransferase-like protein 14 (METTL14). Upon co-transfection with a single guide RNA (sgRNA) plasmid targeting the gene of interest into mammalian cells, it enables RNA methylation regulation of one or multiple target genes.

pCMV-dCas9-TET1

pCMV-dCas9-TET1 is a plasmid that uses the CRISPR/dCas9 gene regulation system to carry out targeted DNA demethylation modification. This plasmid fuses and expresses dCas9 protein with methylcytosine dioxygenase 1 (TET1). After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, DNA methylation regulation of single or multiple target genes can be achieved.

pCMV-dCas9-DNMT3A

pCMV-dCas9-DNMT3A is a plasmid that uses the CRISPR/dCas9 gene regulation system to carry out targeted DNA methylation modification. This plasmid fuses and expresses dCas9 protein and DNA methyltransferase 3α. After co-transfection into mammalian cells with the sgRNA (Single guide RNA) encoding plasmid targeting the target gene, DNA methylation regulation of single or multiple target genes can be achieved.

All Categories - SBS Genetech - for Superior Biology Services since 2000

pCMV-GCaMP6f (fast response calcium ion fluorescent probe)

pCMV-GCaMP6m (moderate kinetics, high sensitivity calcium ion fluorescent probe)

pCMV-GCaMP6s (highly sensitive calcium ion fluorescent probe)

pCMV-Mito-AT1.03 (mitochondrial ATP fluorescent probe)

pCMV-NLS-AT1.03 (nuclear ATP fluorescent probe)

pCMV-AT1.03 (ATP fluorescent probe)

pCMV-dCas9-HDAC3

pCMV-dCas9-HDAC1

pCMV-dCas9-GCN5

pCMV-dCas9-P300

pCMV-dCas9-JMJD2A

pCMV-dCas9-LSD1

pCMV-dCas9-G9a

pCMV-dCas9-SET7/9

pCMV-dCas9-FTO

pCMV-dCas9-ALKBH5

pCMV-dCas9-ALKBH5

pCMV-dCas9-M3-M14

pCMV-dCas9-TET1

pCMV-dCas9-DNMT3A

Precision Molecular Technologies

from Research to Commercial Scale

For over 25 years, SBS Genetech has delivered
high-quality, rigorously validated molecular reagents
trusted by leading research institutions and
biotechnology companies across 60+ countries.

Scientific Validation Behind Our Technologies

We are honored to create value for our customers and facilitate the development of science

All Categories - SBS Genetech - for Superior Biology Services since 2000

pCMV-GCaMP6f (fast response calcium ion fluorescent probe)

pCMV-GCaMP6m (moderate kinetics, high sensitivity calcium ion fluorescent probe)

pCMV-GCaMP6s (highly sensitive calcium ion fluorescent probe)

pCMV-Mito-AT1.03 (mitochondrial ATP fluorescent probe)

pCMV-NLS-AT1.03 (nuclear ATP fluorescent probe)

pCMV-AT1.03 (ATP fluorescent probe)

pCMV-dCas9-HDAC3

pCMV-dCas9-HDAC1

pCMV-dCas9-GCN5

pCMV-dCas9-P300

pCMV-dCas9-JMJD2A

pCMV-dCas9-LSD1

pCMV-dCas9-G9a

pCMV-dCas9-SET7/9

pCMV-dCas9-FTO

pCMV-dCas9-ALKBH5

pCMV-dCas9-ALKBH5

pCMV-dCas9-M3-M14

pCMV-dCas9-TET1

pCMV-dCas9-DNMT3A

Precision Molecular Technologies

from Research to Commercial Scale

For over 25 years, SBS Genetech has delivered high-quality, rigorously validated molecular reagents trusted by leading research institutions and biotechnology companies across 60+ countries.

Scientific Validation Behind Our Technologies

We are honored to create value for our customers and facilitate the development of science

For over 25 years, SBS Genetech has delivered
high-quality, rigorously validated molecular reagents
trusted by leading research institutions and
biotechnology companies across 60+ countries.