
UDP-GlcNAc.2Na
$180.00 - $3,300.00
$4,125.00
Molecular Formula: C17H25N3O17P2Na2
Molecular Weight: 651.32
Purity: 95%, 98%
All products have special prices for bulk purchase, please contact for more details if required.
Cat. No.: UGN2-50-95 (for 50mg, 95% purity)
Cat. No.: UGN2-50-98 (for 50mg, 98% purity)
Cat. No.: UGN2-1k-95 (for 1g, 95% purity)
Cat. No.: UGN2-1k-98 (for 1g, 98% purity)
Description
UDP-GlcNAc.2Na, or uridine diphosphate N-acetylglucosamine disodium salt, is a nucleotide sugar that plays a critical role in glycosylation and carbohydrate metabolism. It is an activated form of N-acetylglucosamine (GlcNAc) and serves as a donor substrate for glycosyltransferase enzymes. These enzymes transfer GlcNAc residues to various acceptor molecules, enabling the biosynthesis of glycans, glycoproteins, and glycolipids.
Features
- Molecular Composition: UDP-GlcNAc consists of a uridine diphosphate (UDP) group linked to N-acetylglucosamine. The disodium salt form enhances its solubility and stability.
- Molecular Formula: C₁₇H₂₅N₃O₁₇P₂·2Na.
- Molecular Weight: Approximately 651.32 g/mol.
Applications
Glycosylation Studies:
- UDP-GlcNAc is a key substrate for glycosyltransferases involved in the synthesis of N-linked and O-linked glycans, which are essential for protein folding, stability, and function.
- It is also used in the study of O-GlcNAcylation, a post-translational modification that regulates cellular processes such as signaling, transcription, and metabolism.
Carbohydrate Metabolism:
- UDP-GlcNAc is a product of the hexosamine biosynthetic pathway, which integrates glucose, amino acids, fatty acids, and nucleotide metabolism.
- It is involved in the biosynthesis of glycosaminoglycans (e.g., hyaluronic acid, heparan sulfate) and glycolipids.
Cellular and Molecular Research:
- Researchers use UDP-GlcNAc to investigate the roles of glycans in cell-cell communication, immune response, and disease progression.
- It is also studied for its role in insulin signaling and glucose sensing.
CAS Number: 91183-98-1
Molecular Formula: C17H25N3O17P2Na2
Molecular Weight: 651.32
Purity: 95%, 98%
Only for research and not intended for treatment of humans or animals
Journals Using SBS Genetech Products Universities Using SBS Genetech Products
SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory