All products have special prices for bulk purchase, please contact us for more details if required.

Explore Versatile Options with Our Glycerol-Free and Lyophilized Variants

Delight in the flexibility of our product offerings, now available in a glycerol-free version, meticulously crafted to seamlessly integrate with your freeze-drying systems. Additionally, we present a lyophilized version, a practical solution ensuring stable transportation at room temperature, thereby notably mitigating shipping costs, especially during long-distance transits.

Cat. No.: THML-100 (for 100 μg)

Cat. No.: THML-500 (for 500 μg)

The lyophilized Tth MutL Protein is also available by inquiry, which can be transported at room temperature.

Description

DNA mismatch repair system (MMR) is mainly composed of three proteins, including MutS, MutL, and MutH. Among them, MutS is responsible for recognizing and binding to mismatched or unbound sites. Subsequently, MutL protein forms a complex with MutS-DNA to enhance its stability, activate the endonuclease activity of MutH, and cooperate with helicase and single-strand binding protein to remove the mismatched sequence. Tth MutL protein is a DNA mismatch repair protein isolated from Thermus thermophilus. It has DNA-dependent ATPase activity in the optimal temperature range of 65-75°C. It can mediate the role of MutS and UVrD in DNA mismatch repair, so it plays an important role in mismatch repair.

Applications

• Conducting mismatch DNA binding experiments with Tth MutS.
• Conducting mismatch DNA enrichment experiments with Tth MutS.
• Conducting mismatch DNA cleavage experiments with Tth MutS.

Storage

The minimum shelf life is 2 years at -20°C.