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Cat. No.: SCPR-0.2 (for 10mM×0.2ml)

Cat. No.: SCPR-25 (for 25mg)

Cat. No.: SCPR-100 (for 100mg)

Description

Scoparone, isolated from Artemisia capillaris, exhibits anticoagulant, vasorelaxant, antioxidant, and anti-inflammatory activities.

Basic Information

• Aliases: 6,7-Dimethylesculetin; 6,7-Dimethoxycoumarin; Escoparone; Scoparin
• Source: Artemisia capillaris Thunb.; Artemisia scoparia Waldst. et Kit.
• Compound type: Phenylpropanoids > Coumarins
• Chemical Formula: C₁₁H₁₀O₄
• Molecular Weight: 206.19
• CAS Number:  120-08-1
• Purity: 98%, HPLC
• Solvent/Solubility: DMSO: 62.5 mg/mL (303.12 mM)
• Solution Preparation: Add 3mg to 1.45ml of DMSO, or alternatively, add 2.06mg to 1ml of DMSO, to prepare a 10mM solution.

Signaling Pathway

Inflammation

In Vitro Study

Scoparone (0-0.4 nM; 24-48 hours) exhibits the highest inhibition of PSC proliferation at 0.4 nM.

In Vivo Study

Scoparone (administered orally at doses of 30 mg/kg and 60 mg/kg for 4 weeks) significantly alleviates pancreatic weight loss induced by DBTC in pancreatitis rats.

Clinical Trial

N/A

Storage

Store at -20°C for at least one year. The solid powder is stable at 4°C for at least one month. If dissolved in a non-DMSO solvent, it is recommended to aliquot and store at -80°C for up to six months.

Precautions

• This product may have a certain degree of toxicity to the human body. Please take appropriate precautions to avoid direct contact with the body or inhalation.
• This product is for scientific research use only by professionals and is not intended for clinical diagnosis or treatment, food, or pharmaceutical purposes. It should not be stored in ordinary residential areas.
• For your safety and health, please wear laboratory attire and disposable gloves while handling.

Only for research and not intended for treatment of humans or animals

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