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Cat. No.: PLGL-0.2 (for 10mM×0.2ml)

Cat. No.: PLGL-5 (for 5mg)

Cat. No.: PLGL-25 (for 25mg)

Description

Polygalaxanthone III, extracted from Polygala tenuifolia wild, exhibits inhibitory effects on CYP450 enzymes. Specifically, it inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1, with an IC50 value of 50.56 μM.

Basic Information

• Aliases: -
• Source: Polygala tenuifolia Willd
• Compound type: Flavonoids > Chalcones
• Chemical Formula: C₂₅H₂₈O₁₅
• Molecular Weight: 568.48
• CAS Number: 162857-78-5
• Purity: 98%, HPLC
• Solvent/Solubility: DMSO: 250 mg/ml (439.77 mM)
• Solution Preparation: 10mg dissolved in 1.76ml of DMSO, or 5.68mg per ml of DMSO, to prepare a 10mM solution.

Signaling Pathway

-

In Vitro Study

In Vivo Study

Clinical Trial

N/A

Storage

Store at -20°C in the dark, stable for at least one year. Store solid powder at 4°C in the dark, stable for at least one month. If dissolved in a non-DMSO solvent, it is recommended to aliquot and store at -80°C in the dark, stable for an estimated six months.

Precautions

• This product may have a certain degree of toxicity to the human body. Please take appropriate precautions to avoid direct contact with the body or inhalation.
• This product is for scientific research use only by professionals and is not intended for clinical diagnosis or treatment, food, or pharmaceutical purposes. It should not be stored in ordinary residential areas.
• For your safety and health, please wear laboratory attire and disposable gloves while handling.

Only for research and not intended for treatment of humans or animals

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