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Cat. No.: LNAC-100-95 (for 100mg, 95% purity)

Cat. No.: LNAC-100-98 (for 100mg, 98% purity)

Cat. No.: LNAC-1k-95 (for 1g, 95% purity)

Cat. No.: LNAC-1k-98 (for 1g, 98% purity)

Description

LacNAc, or N-acetyllactosamine, is a disaccharide composed of galactose (Gal) and N-acetylglucosamine (GlcNAc) linked by a β1,4-glycosidic bond. It is a fundamental building block in glycobiology, commonly found in glycoproteins and glycolipids. LacNAc serves as a precursor for various complex glycans and plays a crucial role in biological recognition processes.

Key Features of LacNAc:

• Biological Role: LacNAc motifs act as ligands for lectins, such as galectins, which are involved in cell-cell communication, immune response, and apoptosis.

• Structural Importance: It forms the backbone of many glycan structures, including Lewis antigens, which are associated with blood group determination and cancer biomarkers.

• Applications: LacNAc is used in research to study glycosylation patterns, develop carbohydrate-based vaccines, and investigate tumor-associated carbohydrate antigens (TACAs).

LacNAc exists in two types:

1. Type I (Galβ1,3GlcNAc): Found in certain glycoproteins and glycolipids.

2. Type II (Galβ1,4GlcNAc): More common and widely studied due to its role in complex glycan synthesis.

CAS Number: 32181-59-2

Molecular Formula: C14H25NO11

Molecular Weight: 383.35

Purity: 95%, 98%

Only for research and not intended for treatment of humans or animals

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