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Cat. No.: HM5CH-25 (for 25μg)

Cat. No.: HM5CH-50 (for 50μg)

Cat. No.: HM5CH-100 (for 100μg)

Description

MUC5AC is a large gel-forming glycoprotein that plays a crucial role in the respiratory tract by protecting against infection. It binds to inhaled pathogens, which are then removed through mucociliary clearance. Overproduction of MUC5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease (COPD). However, increased levels of MUC5AC have also been associated with greater protection against influenza infection.

Species

Human

Molecular Alias

Gastric mucin, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin

Accession

P98088

Expression Sequence

Protein sequence(P98088, Thr2300-Thr2500, with C-10*His)

TTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSGPGTTPSPVPTTSITSAPTTSTTSAPTTSTTSARTSSTTSATTTSRISGPETTPSPVPTTSTTSATTTSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPTTRTTSAPKSSTTSAATTSTTSGPETTPRPVPTTSTGGGGSHHHHHHHHHH

Expression Host

HEK293

Molecular Weight

Theoretical: 20.8kDa 

Actual: 50-180kDa

Purity

＞95% by SDS-PAGE

Endotoxin content

<1 EU/μg

Tag

His Tag

Form

Lyophilized Powder

Buffer System

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

Reconstitution Method

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Storage Conditions

12 months from the date of receipt when stored at -20 to -70 °C as supplied.

6 months at -20 to -70 °C under sterile conditions after reconstitution.

1 week at 2 to 8 °C under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.