Human LAMP1, His tag
$280.00 - $448.00
$560.00
All products have special prices for bulk purchase, please contact us for more details if required.
Cat. No.: HLP1H-50 (for 50μg)
Cat. No.: HLP1H-100 (for 100μg)
Description
Lysosomal-associated membrane protein 1 (LAMP-1), also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein encoded by the LAMP1 gene in humans. This glycoprotein is a type I transmembrane protein expressed at high or medium levels in at least 76 different normal tissue cell types. LAMP-1 is primarily located across lysosomal membranes and provides carbohydrate ligands for selectins. Its expression on the surface of tumor cells has been observed in various cancer types, particularly in highly metastatic cancers such as pancreatic cancer, colon cancer, and melanoma. The structure of LAMP-1 correlates with the differentiation and metastatic potential of tumor cells, as it is thought to mediate cell-cell adhesion and migration.
Species
Human
Molecular Alias
Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, CD107a
Accession
P11279
Expression Sequence
Protein sequence(P11279, ·Ala29-Met382, with C-10*His)
AMFMVKNGNGTACIMANFSAAFSVNYDTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQLMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDATIQAYLSNSSFSRGETRCEQDRPSPTTAPPAPPSPSPSPVPKSPSVDKYNVSGTNGTCLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQFGMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAFSVNIFKVWVQAFKVEGGQFGSVEECLLDENSMGGGGSHHHHHHHHHH
Expression Host
HEK293
Molecular Weight
Theoretical: 40.0kDa
Actual: 75-95kDa
Purity
>95% by SDS-PAGE
Endotoxin content
<1 EU/μg
Label
Unconjugated
Tag
His Tag
Form
Lyophilized Powder
Buffer System
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Method
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Storage Conditions
12 months from the date of receipt, stored at -20 to -70 °C as supplied.
6 months at -20 to -70 °C under sterile conditions after reconstitution.
1 week at 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.