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Cat. No.: HASNH-25 (for 25μg)

Cat. No.: HASNH-50 (for 50μg)

Cat. No.: HASNH-100 (for 100μg)

Description

Alpha-synuclein is a neuronal protein primarily involved in regulating synaptic vesicle trafficking and subsequent neurotransmitter release. Abundant in the brain, it is also found in smaller amounts in the heart, muscle, and other tissues. Within the brain, alpha-synuclein is predominantly located in the axon terminals of presynaptic neurons, where it interacts with phospholipids and proteins. Its function includes restricting the mobility of synaptic vesicles, thereby modulating synaptic vesicle recycling and attenuating neurotransmitter release.

Species

Human

Accession

P37840

Expression Sequence

Protein sequence(P37840 Met1-Ala140, with C-10*His)

MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEAGGGGSHHHHHHHHHH

Expression Host

E.coli

Molecular Weight

Theoretical: 16.1kDa 

Actual: 20kDa

Purity

＞95% by SDS-PAGE

Endotoxin content

<1 EU/μg

Label

Unconjugated

Tag

His Tag

Form

Lyophilized Powder

Buffer System

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

Reconstitution Method

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Storage Conditions

12 months from date of receipt, -20 to -70 °C as supplied.

6 months, -20 to -70 °C under sterile conditions after reconstitution.

1 week, 2 to 8 °C under sterile conditions after reconstitution.  

Please avoid repeated freeze-thaw cycles.