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Cat. No.: GDM2-50-95 (for 50mg, 95% purity)

Cat. No.: GDM2-50-98 (for 50mg, 98% purity)

Cat. No.: GDM2-1k-95 (for 1g, 95% purity)

Cat. No.: GDM2-1k-98 (for 1g, 98% purity)

Description

GDP-D-Man.2Na, or guanosine diphosphate D-mannose disodium salt, is a nucleotide sugar that plays a crucial role in glycosylation and carbohydrate metabolism. It serves as an activated form of D-mannose, a sugar involved in the biosynthesis of glycans, glycoproteins, and glycolipids.

Features

• Molecular Composition: GDP-D-Man.2Na consists of a guanosine diphosphate (GDP) group linked to D-mannose. The disodium salt form enhances its solubility and stability.
• Molecular Formula: C₁₆H₂₃N₅O₁₆P₂Na₂.
• Molecular Weight: Approximately 649.31 g/mol.

Applications

• Glycosylation Studies: GDP-D-Man is a donor substrate for glycosyltransferase enzymes, which transfer mannose residues to acceptor molecules during the synthesis of glycans and glycoconjugates.
• Carbohydrate Metabolism: It plays a role in the biosynthesis of mannose-rich glycans, which are critical for protein folding, stability, and function.
• Enzyme Research: GDP-D-Man is used to study the activity and specificity of enzymes like mannosyltransferases, which are involved in glycosylation pathways.
• Disease Research: Altered levels of GDP-D-Man are associated with certain metabolic disorders, and it is studied to understand its impact on cellular processes.

CAS Number: 103301-73-1

Molecular Formula: C16H23N5Na2O16P2

Molecular Weight: 649.31

Purity: 95%, 98%

Only for research and not intended for treatment of humans or animals

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