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Cat. No.: GAN-50 (for 50mg)

Cat. No.: GAN-1k (for 1g)

Description

GalNAz, or N-azidoacetylgalactosamine, is a chemical compound derived from N-acetylgalactosamine (GalNAc). It plays a vital role in bioorthogonal chemistry and glycobiology research, particularly in the labeling and visualization of glycoconjugates.

This molecule contains an azide group, which makes it reactive in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC). These reactions allow GalNAz to be tagged with fluorescent dyes, biotin, or other probes for tracking and studying glycosylation processes.

When introduced to cells, GalNAz is metabolically incorporated into glycoproteins and glycolipids, replacing natural GalNAc residues. This metabolic labeling enables researchers to investigate the roles of glycoconjugates in various biological processes, including cell signaling, immune response, and disease progression.

GalNAz is often preferred in studies due to its bioorthogonal nature, meaning it does not interfere with native cellular processes. It is commonly used in applications like proteomics, cellular imaging, and biomarker discovery, providing insights into the complex world of cellular glycosylation.

CAS Number: 869186-83-4

Molecular Formula: C8H14N4O6

Molecular Weight: 262.22

Purity: 98%

Only for research and not intended for treatment of humans or animals

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