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Cat. No.: A4GN-100 (for 100mg)

Cat. No.: A4GN-1k (for 1g)

Description

Ac4GlcNAz, or N-azidoacetylglucosamine-tetraacylated, is a chemical reagent widely used in glycobiology and bioorthogonal chemistry. It is a derivative of N-acetylglucosamine (GlcNAc), a sugar involved in glycosylation processes. Ac4GlcNAz is particularly valuable for studying glycoproteins and glycoconjugates.

This compound contains an azide group, which enables it to participate in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC). These reactions allow for the selective labeling and visualization of glycoconjugates.

When introduced into cells, Ac4GlcNAz is metabolically incorporated into glycoproteins and glycolipids, replacing natural GlcNAc with azide-functionalized analogs. This makes it a powerful tool for tracking glycosylation, studying cellular processes, and investigating the roles of glycoconjugates in health and disease.

Ac4GlcNAz is cell-permeable and is processed intracellularly. It is typically stored at -20°C and is soluble in solvents like DMSO, DMF, and methanol. Its molecular formula is C₁₆H₂₂N₄O₁₀, with a molecular weight of 430.37 g/mol.

CAS Number: 98924-81-3

Molecular Formula: C16H22N4O10

Molecular Weight: 430.37

Purity: 98%

Only for research and not intended for treatment of humans or animals

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