Description

Keratinocyte growth factor (KGF), also known as FGF-7, is a cytokine discovered by Rubin et al. (1989) in the conditioned medium of embryonic lung fibroblast cultures. KGF is secreted by stromal cells, with its receptors located on epithelial cells. It is an effective epithelial cell-specific growth factor, primarily exhibiting mitogenic activity in keratinocytes. KGF specifically promotes the proliferation, migration, and differentiation of epithelial cells and is closely related to various processes, including organ development, wound healing, tumorigenesis, and immune reconstitution.

OsrhKGF is produced using recombinant gene technology, expressed in rice endosperm cells, and purified through protein extraction processes.

Specifications

• Source: Rice seeds
• Appearance: White lyophilized powder
• Purity: ≥95% (SDS-PAGE)
• Activity: ≥1.0×10^6 IU/mg
• pH: 6.5-8.0
• Molecular Weight: 19.0 kD
• Endotoxin: ≤0.1 EU/µg
• CAS No: 148348-15-6

Storage Conditions

• Storage: Store at -20°C
• Stability: Over 36 months

Precautions
Reconstitution: It is recommended to reconstitute OsrhKGF lyophilized powder in sterile water to 100-200 µg/ml, with further dilution possible using other solvents. The reconstituted OsrhKGF can be stored at 4°C for 2-7 days; use as soon as possible, and store at -20°C if not used shortly.

Use promptly after opening to avoid contamination.

Usage Limitations
For research, laboratory, and production use only; not for direct human use.

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