Description

Human epidermal growth factor (EGF) has a molecular weight of 6.2 kD and consists of 53 amino acids, featuring three disulfide bonds. Upon binding to its specific receptor EGFR on the cell surface, EGF triggers a series of biochemical reactions within the cell: it increases intracellular calcium ion concentration, promotes glycolysis, enhances protein synthesis, and boosts the expression of specific genes related to EGFR, thereby promoting DNA synthesis and cell proliferation.

Specifications

• Source: Pichia pastoris
• Appearance: White lyophilized powder
• Purity: ≥98% (SDS-PAGE)
• Activity: ≥1.0×10^6 IU/mg
• Molecular Weight: 6.2 kD
• Endotoxin: ≤1.0 EU/mg
• CAS No: 62253-63-8

Storage Conditions

• Storage: Store at -20°C
• Stability: Over 36 months

Precautions
Reconstitution: It is recommended to reconstitute rhEGF lyophilized powder in sterile water to 100-200 μg/ml, with further dilution possible using other solvents. The reconstituted rhEGF can be stored at 4°C for 2-7 days; use as soon as possible, and store at -20°C if not used shortly. Use promptly after opening to avoid contamination.

Usage Limitations
For research, laboratory, and production use only; not for direct human use.

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