Exosome refers to cup-shaped vesicles with a diameter ranging from 30 to 150 nm. These vesicles encapsulate various substances such as proteins, mRNA, and microRNA. Exosomes can be secreted by various cells under normal and pathological conditions and are present in various body fluids, including blood, saliva, urine, cerebrospinal fluid, and breast milk. The functions of exosomes depend on the cell types they originate from and can be involved in various aspects of the body's immune response, antigen presentation, cell migration, cell differentiation, tumor invasion, and more. 

Under normal circumstances, untreated exosomes maintained at 4°C can only preserve their structural integrity for approximately 10 days. Although they can be stored for an extended period at -80°C, this storage condition requires expensive equipment, occupies substantial space, and is inconvenient for transportation. Therefore, -80°C is not an ideal long-term storage condition for exosomes.

We have developed an exosome lyophilization protection agent. After vacuum freeze-drying, the resulting exosome lyophilized powder can be stored for an extended period at 4°C. Upon reconstitution, it retains the original exosome morphology and biological activity, making it a highly practical method for long-term exosome storage.

Product Catalog

• Human Plasma Exosomes
• Human Serum Exosomes
• Human Urine Exosomes
• Human Saliva Exosomes
• Milk Exosomes
• Ginger Tissue Exosomes
• Adipose-Derived Mesenchymal Stem Cell Exosomes
• Umbilical Cord Mesenchymal Stem Cell Exosomes
• Bone Marrow Mesenchymal Stem Cell Exosomes
• HEK293 Exosomes

Storage

This product is shipped at low temperatures and can be stored for at least 12 months at 2-8°C. Upon reconstitution, it is recommended to use it within one week when stored at 2-8°C, one month at -20°C, or six months at -80°C, to avoid repeated freeze-thaw cycles.

Product Customization

We not only offer research-grade exosome purification and lyophilization products and services, but also provide a variety of exosome extraction kits and lyophilized protective solutions. Additionally, we have independently developed a rapid and automated exosome purification instrument.

For research users, we can process various sample types, including cell culture supernatants, urine, serum, or blood. You can choose extraction and purification kits of different specifications based on sample type and volume. After obtaining exosomes, you can perform BCA and NTA measurements. We also offer additional assays upon request, such as transmission electron microscopy, ELISA, nucleic acid extraction and detection (RT-qPCR or NGS), and protein extraction and detection (Western Blot or mass spectrometry).

For industrial users, particularly those in the fields of regenerative medicine and drug delivery research, we provide extraction services for large volumes of various cell culture supernatants.