We are proud to offer custom miRNA and siRNA with our professional synthesis and purification technology.
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We can provide as short as 2 nt DNA/RNA synthesis services to as long as 200 nt DNA, 70 nt RNA synthesis services.
We can provide various DNA/RNA modifications.
We provide both mass spectrometry and Waters high-performance liquid chromatography analysis. You can use our custom miRNA with confidence.
We can provide synthesis services from microgram to hundreds of grams.
Turnaround time is short. For routine modifications, only 2-3 working days are needed for the synthesis and purification.
The purity of clinical test grade is more than 99%, with high stability and no cross-contamination.
DNA: The DNA dry powder is stable and can be stored at -20 C for 2 years. Dissolution of DNA can be done with sterile water or TE, and the dissolved DNA is best stored at -20 C. Repeated freeze-thaw should be avoided.
RNA: Because the stability of RNA is much worse than that of DNA, it is recommended that the RNA be stored at -80 C in either dry powder or solution state, and the RNA in solution state should be avoided from repeated freezing and thawing. Modified oligonucleotides are recommended to be stored up to -20 C, and fluorescent modifications need to be kept away from light.
The base sequences of miRNA-126, cDNA, single-base mismatched miRNA-126 (MM1), double-base mismatched miRNA-126 (MM2), and other kinds of miRNAs, obtained from SBS Genetech Co. Ltd., are shown as follows
Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis
A PKC specific siRNA (the target sequence was: 5′-GATCCGTTACTGACAGGCATTATA-3′) and the control siRNA (the target sequence was: 5′-GCCCGAGTCCCATCGAAACCTCAA-3′) were purchased from SBS Genetech (Bei Jing, China).
Only for research and not intended for treatment of humans or animals